Synthesis of pyrazolo- and [1,2,4]triazolo-[1,5-a]quinolin-9-ols by cycloaddition to 8-hydroxyquinoline N-imide

被引：8

作者：

Evtushok, Vasilii E. ^{[1
]}

Vorob'ev, Aleksey Yu. ^{[2
,3
]}

机构：

[1] Russian Acad Sci, Siberian Branch, Boreskov Inst Catalysis, 5 Akad Lavrentieva Ave, Novosibirsk 630090, Russia

[2] Russian Acad Sci, Siberian Branch, NN Vorozhtsov Novosibirsk Inst Organ Chem, 9 Akad Lavrentieva Ave, Novosibirsk 630090, Russia

[3] Novosibirsk State Univ, 1 Pirogova St, Novosibirsk 630090, Russia

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2019年 / 55卷 / 03期

基金：

俄罗斯科学基金会;

关键词：

8-hydroxyquinoline; N-imines; pyrazolo[1; 5-a]quinoline; 1; 2; 4]triazolo[1; 1,3-dipolar cycloaddition; 1,3-DIPOLAR CYCLOADDITION; DERIVATIVES; IMINES; CHEMOSENSOR; COMPLEXES; CHEMISTRY; SCAFFOLD;

D O I：

10.1007/s10593-019-02446-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of 1-amino-8-hydroxyquinolinium mesitylenesulfonate with alkenes and alkynes containing electron-withdrawing substituents was performed in MeCN-K2C?(3) system and gave the respective 9-hydroxypyrazolo[1,5-a]quinolines. The reaction with acetonitrile\ and aromatic nitriles in aqueous 2 N K?H solution gave the respective 2-substituted 9-hydroxy[1,2,4]triazolo[1,5-a]quinolines.

引用

页码：229 / 234

页数：6

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