PET: Is myocardial flow quantification a clinical reality?

被引：59

作者：

Saraste, Antti ^{[1
,2
]}

Kajander, Sami ^{[1
]}

Han, Chunlei ^{[1
]}

Nesterov, Sergey V. ^{[1
]}

Knuuti, Juhani ^{[1
]}

机构：

[1] Univ Turku, Turku PET Ctr, FIN-20520 Turku, Finland

[2] Turku Univ Hosp, Dept Med, FIN-20520 Turku, Finland

来源：

JOURNAL OF NUCLEAR CARDIOLOGY | 2012年 / 19卷 / 05期

基金：

芬兰科学院;

关键词：

PET imaging; ischemia; myocardial; myocardial perfusion imaging: PET; CORONARY-ARTERY-DISEASE; POSITRON-EMISSION-TOMOGRAPHY; OPTIMAL MEDICAL THERAPY; BLOOD-FLOW; PROGNOSTIC VALUE; N-13; AMMONIA; RB-82; PET; NONINVASIVE QUANTIFICATION; ABSOLUTE QUANTIFICATION; COMPUTED-TOMOGRAPHY;

D O I：

10.1007/s12350-012-9588-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Positron emission tomography (PET) enables quantitative measurements of myocardial blood flow (MBF) and myocardial flow reserve (MFR). Recent developments and improved availability of PET technology have resulted in growing interest in translation of quantitative flow analysis from mainly a research tool to routine clinical practice. Quantitative PET measurements of absolute MBF and MFR have potential to improve accuracy of myocardial perfusion imaging in diagnosis of multivessel coronary artery disease as well as definition of the extent and functional importance of stenoses. This article reviews recent advances and experience in the quantitative myocardial perfusion imaging together with issues that need to be resolved for quantitative analysis to become clinical reality.

引用

页码：1044 / 1059

页数：16

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