G protein-coupled estrogen receptor: A new therapeutic target in stroke and traumatic brain/spinal cord injury?

被引：9
作者：
Prossnitz, Eric R. [1 ]
机构：
[1] Univ New Mexico, Hlth Sci Ctr, UNM Canc Ctr, Dept Cell Biol & Physiol, Albuquerque, NM 87131 USA
来源：
CRITICAL CARE MEDICINE | 2012年 / 40卷 / 12期
关键词：
estrogen; G-protein coupled receptor 30; inflammation; neuroprotection; neurotrauma; RATS; AGONIST; DISEASE; GPR30; GPER;
D O I：
10.1097/CCM.0b013e31826be998
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
引用
收藏
页码：3323 / 3325
页数：4
相关论文
共 21 条
[1]   Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis [J].
Blasko, Eric ;
Haskell, Christopher A. ;
Leung, Stewart ;
Gualtieri, Giovanna ;
Halks-Miller, Meredith ;
Mahmoudi, Mithra ;
Dennis, Megan K. ;
Prossnitz, Eric R. ;
Karpus, William J. ;
Horuk, Richard .
JOURNAL OF NEUROIMMUNOLOGY, 2009, 214 (1-2) :67-77
[2]   Virtual and biomolecular screening converge on a selective agonist for GPR30 [J].
Bologa, CG ;
Revankar, CM ;
Young, SM ;
Edwards, BS ;
Arterburn, JB ;
Kiselyov, AS ;
Parker, MA ;
Tkachenko, SE ;
Savchuck, NP ;
Sklar, LA ;
Oprea, TI ;
Prossnitz, ER .
NATURE CHEMICAL BIOLOGY, 2006, 2 (04) :207-212
[3]   Induction of interleukin-10 in the T helper type 17 effector population by the G protein coupled estrogen receptor (GPER) agonist G-1 [J].
Brunsing, Ryan L. ;
Prossnitz, Eric R. .
IMMUNOLOGY, 2011, 134 (01) :93-106
[4]  
Carroll JC, 2012, CURR ALZHEIMER RES, V9, P18
[5]  
*CDCP, SPIN CORD INJ SCI FA
[6]   Regulation of signal transduction pathways by estrogen and progesterone [J].
Edwards, DP .
ANNUAL REVIEW OF PHYSIOLOGY, 2005, 67 :335-376
[7]   Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF [J].
Filardo, EJ ;
Quinn, JA ;
Bland, KI ;
Frackelton, AR .
MOLECULAR ENDOCRINOLOGY, 2000, 14 (10) :1649-1660
[8]   G-protein coupled estrogen receptor 1 mediated estrogenic neuroprotection against spinal cord injury [J].
Hu, Rong ;
Sun, Haodong ;
Zhang, Qian ;
Chen, Jingyu ;
Wu, Nan ;
Meng, Hui ;
Cui, Gaoyu ;
Hu, Shengli ;
Li, Fei ;
Lin, Jiangkai ;
Wan, Qi ;
Feng, Hua .
CRITICAL CARE MEDICINE, 2012, 40 (12) :3230-3237
[9]   Neuroprotective effects of tamoxifen on experimental spinal cord injury in rats [J].
Ismailoglu, Ozguer ;
Oral, Baha ;
Gorgulu, Askin ;
Sutcu, Recep ;
Demir, Necdet .
JOURNAL OF CLINICAL NEUROSCIENCE, 2010, 17 (10) :1306-1310
[10]   A Systematic Review of Directly Applied Biologic Therapies for Acute Spinal Cord Injury [J].
Kwon, Brian K. ;
Okon, Elena B. ;
Plunet, Ward ;
Baptiste, Darryl ;
Fouad, Karim ;
Hillyer, Jessica ;
Weaver, Lynne C. ;
Fehlings, Michael G. ;
Tetzlaff, Wolfram .
JOURNAL OF NEUROTRAUMA, 2011, 28 (08) :1589-1610
123