A case of transient existence of SARS-CoV-2 RNA in the respiratory tract with the absence of anti-SARS-CoV-2 antibody response

被引：14

作者：

Lin, Yi-Chun ^{[1
,2
]}

Cheng, Chien-Yu ^{[1
,3
]}

Chen, Cheng-Pin ^{[1
,4
]}

Cheng, Shu-Hsing ^{[1
,5
]}

Chang, Sui-Yuan ^{[6
,7
]}

Hsueh, Po-Ren ^{[7
,8
]}

机构：

[1] Taoyuan Gen Hosp, Dept Internal Med, Div Infect Dis, Minist Hlth & Welf, Taoyuan, Taiwan

[2] Taipei Med Univ, Coll Med, Grad Inst Clin Med, Taipei, Taiwan

[3] Natl Yang Ming Univ, Sch Publ Hlth, Taipei, Taiwan

[4] Natl Yang Ming Univ, Inst Clin Med, Taipei, Taiwan

[5] Taipei Med Univ, Sch Publ Hlth, Taipei, Taiwan

[6] Natl Taiwan Univ, Dept Clin Lab Sci & Med Biotechnol, Coll Med, Taipei, Taiwan

[7] Natl Taiwan Univ, Natl Taiwan Univ Hosp, Dept Lab Med, Coll Med, Taipei, Taiwan

[8] Natl Taiwan Univ, Natl Taiwan Univ Hosp, Dept Internal Med, Coll Med, Taipei, Taiwan

来源：

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES | 2020年 / 96卷

关键词：

COVID-19; SARS-CoV-2; Asymptomatic infection; Colonization; Contamination;

D O I：

10.1016/j.ijid.2020.05.070

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We report the case of a patient who had travelled to Japan and who presented mild respiratory symptoms during the COVID-19 outbreak period. There was transient existence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in his oropharynx. The RNA was absent in the six respiratory specimens that were subsequently tested. An anti-SARS-CoV-2 antibody response was absent in the acute and convalescent sera. The reported case indicates that transient colonization of SARS-CoV-2 in the upper respiratory tract is possible without inciting any antibody response against the virus. (C) 2020 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.

引用

页码：464 / 466

页数：3

共 50 条

[41] Coinfection between SARS-CoV-2 and other respiratory tract viruses
Ozdemir, Oner
Dikici, Ummugulsum
JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2022, 36 (06)
[42] The Upper Respiratory Tract Microbiome Network Impacted by SARS-CoV-2
Li, Wendy
Ma, Zhanshan
MICROBIAL ECOLOGY, 2023, 86 (02) : 1428 - 1437
[43] Antibody response to SARS-CoV-2 in people living with HIV
Yamamoto, Shinya
Saito, Makoto
Nagai, Etsuko
Toriuchi, Keiko
Nagai, Hiroyuki
Yotsuyanagi, Hiroshi
Nakagama, Yu
Kido, Yasutoshi
Adachi, Eisuke
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION, 2021, 54 (01) : 144 - 146
[44] Upper respiratory tract SARS-CoV-2 RNA loads in symptomatic and asymptomatic children and adults
Costa, Rosa
Bueno, Felipe
Albert, Eliseo
Torres, Ignacio
Carbonell-Sahuquillo, Silvia
Barres-Fernandez, Ana
Sanchez, David
Padron, Carmelo
Colomina, Javier
Carreno, Maria Isabel Lazaro
Breton-Martinez, Jose Rafael
Martinez-Costa, Cecilia
Navarro, David
CLINICAL MICROBIOLOGY AND INFECTION, 2021, 27 (12) : 1858.e1 - 1858.e7
[45] The Upper Respiratory Tract Microbiome Network Impacted by SARS-CoV-2
Wendy Li
Zhanshan (Sam) Ma
Microbial Ecology, 2023, 86 : 1428 - 1437
[46] Respiratory Coinfections in Children With SARS-CoV-2
Westbrook, Adrianna
Wang, Tingyu
Bhakta, Kushmita
Sullivan, Julie
Gonzalez, Mark D.
Lam, Wilbur
Rostad, Christina A.
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2023, 42 (09) : 774 - 780
[47] Anti-SARS-CoV-2 Omicron Antibodies Isolated from a SARS-CoV-2 Delta Semi-Immune Phage Display Library
Mendoza-Salazar, Ivette
Gomez-Castellano, Keyla M.
Gonzalez-Gonzalez, Edith
Gamboa-Suasnavart, Ramses
Rodriguez-Luna, Stefany D.
Santiago-Casas, Giovanni
Cortes-Paniagua, Maria, I
Perez-Tapia, Sonia M.
Almagro, Juan C.
ANTIBODIES, 2022, 11 (01)
[48] Antibody-dependent enhancement (ADE) of SARS-CoV-2 in patients exposed to MERS-CoV and SARS-CoV-2 antigens
Thomas, Swapna
Smatti, Maria K.
Alsulaiti, Haya
Zedan, Hadeel T.
Eid, Ali H.
Hssain, Ali A.
Abu Raddad, Laith J.
Gentilcore, Giusy
Ouhtit, Allal
Althani, Asmaa A.
Nasrallah, Gheyath K.
Grivel, Jean-Charles
Yassine, Hadi M.
JOURNAL OF MEDICAL VIROLOGY, 2024, 96 (05)
[49] Detection of SARS-CoV-2 by Use of the Cepheid Xpert Xpress SARS-CoV-2 and Roche cobas SARS-CoV-2 Assays
Moran, Angelica
Beavis, Kathleen G.
Matushek, Scott M.
Ciaglia, Carol
Francois, Nina
Tesic, Vera
Love, Nedra
JOURNAL OF CLINICAL MICROBIOLOGY, 2020, 58 (08)
[50] A Possible Case of Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a Newborn With Positive Placental In Situ Hybridization of SARS-CoV-2 RNA
Alamar, Ihab
Abu-Arja, Mohammad H.
Heyman, Taryn
Roberts, Drucilla J.
Desai, Niyati
Narula, Pramod
Dygulska, Beata
JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY, 2020, 9 (05) : 636 - 639

← 1 2 3 4 5 →