A case of transient existence of SARS-CoV-2 RNA in the respiratory tract with the absence of anti-SARS-CoV-2 antibody response

被引：14

作者：

Lin, Yi-Chun ^{[1
,2
]}

Cheng, Chien-Yu ^{[1
,3
]}

Chen, Cheng-Pin ^{[1
,4
]}

Cheng, Shu-Hsing ^{[1
,5
]}

Chang, Sui-Yuan ^{[6
,7
]}

Hsueh, Po-Ren ^{[7
,8
]}

机构：

[1] Taoyuan Gen Hosp, Dept Internal Med, Div Infect Dis, Minist Hlth & Welf, Taoyuan, Taiwan

[2] Taipei Med Univ, Coll Med, Grad Inst Clin Med, Taipei, Taiwan

[3] Natl Yang Ming Univ, Sch Publ Hlth, Taipei, Taiwan

[4] Natl Yang Ming Univ, Inst Clin Med, Taipei, Taiwan

[5] Taipei Med Univ, Sch Publ Hlth, Taipei, Taiwan

[6] Natl Taiwan Univ, Dept Clin Lab Sci & Med Biotechnol, Coll Med, Taipei, Taiwan

[7] Natl Taiwan Univ, Natl Taiwan Univ Hosp, Dept Lab Med, Coll Med, Taipei, Taiwan

[8] Natl Taiwan Univ, Natl Taiwan Univ Hosp, Dept Internal Med, Coll Med, Taipei, Taiwan

来源：

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES | 2020年 / 96卷

关键词：

COVID-19; SARS-CoV-2; Asymptomatic infection; Colonization; Contamination;

D O I：

10.1016/j.ijid.2020.05.070

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We report the case of a patient who had travelled to Japan and who presented mild respiratory symptoms during the COVID-19 outbreak period. There was transient existence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in his oropharynx. The RNA was absent in the six respiratory specimens that were subsequently tested. An anti-SARS-CoV-2 antibody response was absent in the acute and convalescent sera. The reported case indicates that transient colonization of SARS-CoV-2 in the upper respiratory tract is possible without inciting any antibody response against the virus. (C) 2020 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.

引用

页码：464 / 466

页数：3

共 50 条

[21] Preliminary Evaluation of QuantiFERON SARS-CoV-2 and QIAreach Anti-SARS-CoV-2 Total Test in Recently Vaccinated Individuals
Soumya Jaganathan
Francis Stieber
Sonia N. Rao
Vladyslav Nikolayevskyy
Davide Manissero
Nadia Allen
Jeff Boyle
Jenny Howard
Infectious Diseases and Therapy, 2021, 10 : 2765 - 2776
[22] Preliminary Evaluation of QuantiFERON SARS-CoV-2 and QIAreach Anti-SARS-CoV-2 Total Test in Recently Vaccinated Individuals
Jaganathan, Soumya
Stieber, Francis
Rao, Sonia N.
Nikolayevskyy, Vladyslav
Manissero, Davide
Allen, Nadia
Boyle, Jeff
Howard, Jenny
INFECTIOUS DISEASES AND THERAPY, 2021, 10 (04) : 2765 - 2776
[23] SARS-CoV-2 Mpro inhibitors: identification of anti-SARS-CoV-2 Mpro compounds from FDA approved drugs
Bharadwaj, Shiv
Azhar, Esam Ibraheem
Kamal, Mohammad Amjad
Bajrai, Leena Hussein
Dubey, Amit
Jha, Kanupriya
Yadava, Umesh
Kang, Sang Gu
Dwivedi, Vivek Dhar
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2022, 40 (06) : 2769 - 2784
[24] Multicentre Performance Evaluation of the Elecsys Anti-SARS-CoV-2 Immunoassay as an Aid in Determining Previous Exposure to SARS-CoV-2
Elena Riester
Mario Majchrzak
Annelies Mühlbacher
Caroline Tinguely
Peter Findeisen
Johannes Kolja Hegel
Michael Laimighofer
Christopher M. Rank
Kathrin Schönfeld
Florina Langen
Tina Laengin
Christoph Niederhauser
Infectious Diseases and Therapy, 2021, 10 : 2381 - 2397
[25] Are anti-SARS-CoV-2 S/N IgG/IgM antibodies always predictive of previous SARS-CoV-2 infection?
Lippi, Giuseppe
Henry, Brandon M.
Pighi, Laura
De Nitto, Simone
Salvagno, Gian Luca
ADVANCES IN LABORATORY MEDICINE-AVANCES EN MEDICINA DE LABORATORIO, 2023, 4 (02): : 175 - 179
[26] Plasma SARS-CoV-2 RNA Levels as a Biomarker of Lower Respiratory Tract SARS-CoV-2 Infection in Critically Ill Patients With COVID-19
Jacobs, Jana L.
Naqvi, Asma
Shah, Faraaz A.
Boltz, Valerie F.
Kearney, Mary F.
McVerry, Bryan J.
Ray, Prabir
Schaefer, Caitlin
Fitzpatrick, Meghan
Methe, Barbara
Lee, Janet S.
Morris, Alison
Mellors, John W.
Kitsios, Georgios D.
Bain, William
JOURNAL OF INFECTIOUS DISEASES, 2022, : 2089 - 2094
[27] The Impact of SARS-CoV-2 on Work Absence
Etli, Dominic
Wiewior, Antonina
Malone, Alex
Locke, Ken
Bullock, Nicholas
Howard, Raina
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 2025, 67 (03) : e139 - e151
[28] Existence of SARS-Cov-2 in the Peritoneal Fluid
Ilgen, Orkun
Ozgozen, Mehmet Eyuphan
Appak, Ozgur
Ertan, Begum
Timur, Hikmet Tunc
Dogan, Omer Erbil
Posaci, Cemal
REVISTA BRASILEIRA DE GINECOLOGIA E OBSTETRICIA, 2023, 45 (05): : 261 - 265
[29] Successful Anti-SARS-CoV-2 Spike Protein Antibody Response to Vaccination in MAGTI Deficiency
Jalil, Maaz
Rowane, Marija
Rajan, Jayanth
Hostoffer, Robert, Jr.
ALLERGY & RHINOLOGY, 2021, 12
[30] Anti-SARS-CoV-2 Potential of Artemisinins In Vitro
Cao, Ruiyuan
Hu, Hengrui
Li, Yufeng
Wang, Xi
Xu, Mingyue
Liu, Jia
Zhang, Huanyu
Yan, Yunzheng
Zhao, Lei
Li, Wei
Zhang, Tianhong
Xiao, Dian
Guo, Xiaojia
Li, Yuexiang
Yang, Jingjing
Hu, Zhihong
Wang, Manli
Zhong, Wu
ACS INFECTIOUS DISEASES, 2020, 6 (09): : 2524 - 2531

← 1 2 3 4 5 →