Increased activity of histone deacetylases in childhood acute lymphoblastic leukaemia and acute myeloid leukaemia: support for histone deacetylase inhibitors as antileukaemic agents

被引:20
|
作者
Sonnemann, Juergen [1 ]
Gruhn, Bernd [1 ]
Wittig, Susan [1 ]
Becker, Sabine [1 ]
Beck, James F. [1 ]
机构
[1] Jena Univ Hosp, Dept Paediat Haematol & Oncol, Childrens Clin, Jena, Germany
关键词
histone deacetylase inhibitor; histone acetyltransferase; acute lymphoblastic leukaemia; acute myeloid leukaemia; paediatric; EXPRESSION; MUTATIONS; GENES;
D O I
10.1111/j.1365-2141.2012.09187.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:664 / 666
页数:3
相关论文
共 50 条
  • [1] Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors
    C A Bradbury
    F L Khanim
    R Hayden
    C M Bunce
    D A White
    M T Drayson
    C Craddock
    B M Turner
    Leukemia, 2005, 19 : 1751 - 1759
  • [2] Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors
    Bradbury, C
    Khanim, F
    Hayden, R
    Bunce, CM
    White, DA
    Drayson, MT
    Craddock, C
    Turner, BM
    LEUKEMIA, 2005, 19 (10) : 1751 - 1759
  • [3] Characterisation of histone deacetylase (HDAC) expression profiles in acute myeloid leukaemia: A basis for the development of targeted therapy using histone deacetylase inhibitors
    Bradbury, CA
    Khanim, FL
    Mehta, P
    Hayden, RE
    Craddock, CF
    Bunce, CM
    Turner, BM
    BLOOD, 2004, 104 (11) : 318A - 318A
  • [4] Role of the histone deacetylase complex in acute promyelocytic leukaemia
    Lin, RJ
    Nagy, L
    Inoue, S
    Shao, WL
    Miller, WH
    Evans, RM
    NATURE, 1998, 391 (6669) : 811 - 814
  • [5] Role of the histone deacetylase complex in acute promyelocytic leukaemia
    Richard J. Lin
    Laszlo Nagy
    Satoshi Inoue
    Wenlin Shao
    Wilson H. Miller
    Ronald M. Evans
    Nature, 1998, 391 : 811 - 814
  • [6] A specific pattern of histone deacetylase (HDAC) expression can be identified in acute myeloid leukaemia: Relevance for targeted therapy with histone cleacetylase inhibitors
    Bradbury, CA
    Khanim, FL
    Mehta, P
    Hayden, RE
    Craddock, CF
    Bunce, CM
    Turner, BM
    BRITISH JOURNAL OF HAEMATOLOGY, 2005, 129 : 30 - 30
  • [8] Epigenetic therapies in acute myeloid leukemia: the role of hypomethylating agents, histone deacetylase inhibitors and the combination of hypomethylating agents with histone deacetylase inhibitors
    Xu Qing-Yu
    Yu, Li
    CHINESE MEDICAL JOURNAL, 2020, 133 (06) : 699 - 715
  • [9] Histone deacetylase inhibitors potently repress CXCR4 chemokine receptor expression and function in acute lymphoblastic leukaemia
    Crazzolara, R
    Jöhrer, K
    Johnstone, RW
    Greil, R
    Kofler, R
    Meister, B
    Bernhard, D
    BRITISH JOURNAL OF HAEMATOLOGY, 2002, 119 (04) : 965 - 969
  • [10] Childhood acute lymphoblastic leukaemia
    Henze, G
    EUROPEAN JOURNAL OF CANCER, 1997, 33 (01) : 8 - 9