Brain Abscesses Due to Aspergillus nidulans Infection During Induction Chemotherapy for Acute Lymphoblastic Leukemia

被引：13
作者：
Sadarangani, Manish [1 ,4 ]
Harvey, Melissa [2 ]
McDonald, Allison [3 ]
Speert, David P. [1 ,3 ]
Dix, David [2 ]
机构：
[1] Univ British Columbia, Dept Paediat, Div Infect Dis, Vancouver, BC, Canada
[2] Univ British Columbia, Dept Paediat, Div Hematol & Oncol, Vancouver, BC, Canada
[3] Child & Family Res Inst, Vancouver, BC, Canada
[4] Univ Oxford, Dept Paediat, Oxford OX3 9DU, England
来源：
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2015年 / 37卷 / 06期
关键词：
acute lymphoblastic leukemia; aspergillosis; cerebral abscess; chemotherapy; fungal; INVASIVE FUNGAL-INFECTIONS; EPIDEMIOLOGY; CHILDREN; VORICONAZOLE; COMBINATION; ANTIFUNGAL; CANCER;
D O I：
10.1097/MPH.0000000000000351
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
We present the case of a 3-year-old boy who was diagnosed with cerebral abscesses due to Aspergillus nidulans infection on day 28 of induction chemotherapy for acute lymphoblastic leukemia. He responded well to treatment with voriconazole and caspofungin, making a full recovery. There are very few cases of invasive aspergillosis reported in children during induction chemotherapy for acute leukemia and A. nidulans is rare in the absence of chronic granulomatous disease.
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收藏
页码：e384 / e386
页数：3
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