Superhydrophobic Surfaces as a Tool for the Fabrication of Hierarchical Spherical Polymeric Carriers

被引：25
|
作者：
Costa, Ana M. S. [1 ]
Alatorre-Meda, Manuel [1 ,2 ]
Alvarez-Lorenzo, Carmen [3 ]
Mano, Joao F. [1 ]
机构：
[1] Univ Minho, ICVS PT Govt Associate Lab 3Bs, Res Grp Biomat Biodegradables & Biomimet Headquar, European Inst Excellence Tissue Engn & Regenerat, P-4805017 Barco, Gmr, Portugal
[2] Inst Tecnol Tijuana, Catedras CONACyT Comisionado, Ctr Grad & Invest Quim, Tijuana 22510, BC, Mexico
[3] Univ Santiago de Compostela, Fac Farm, Dept Farm & Tecnol Farmaceut, Santiago De Compostela 15782, Spain
来源：
SMALL | 2015年 / 11卷 / 30期
关键词：
biomaterials; cell encapsulation; drug delivery; hierarchical carriers; superhydrophobic surfaces; HYDROGEL CAPSULES; ALGINATE; DELIVERY; ENCAPSULATION; PARTICLES; RELEASE; MATRIX;
D O I：
10.1002/smll.201500192
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Hierarchical polymeric carriers with high encapsulation efficiencies are fabricated via a biocompatible strategy developed using superhydrophobic (SH) surfaces. The carries are obtained by the incorporation of cell/BSA-loaded dextran-methacrylate (DEXT-MA) microparticles into alginate (ALG) macroscopic beads. Engineered devices like these are expected to boost the development of innovative and customizable systems for biomedical and biotechnological purposes. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：3648 / 3652
页数：5
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