Superhydrophobic Surfaces as a Tool for the Fabrication of Hierarchical Spherical Polymeric Carriers

被引：26

作者：

Costa, Ana M. S. ^{[1
]}

Alatorre-Meda, Manuel ^{[1
,2
]}

Alvarez-Lorenzo, Carmen ^{[3
]}

Mano, Joao F. ^{[1
]}

机构：

[1] Univ Minho, ICVS PT Govt Associate Lab 3Bs, Res Grp Biomat Biodegradables & Biomimet Headquar, European Inst Excellence Tissue Engn & Regenerat, P-4805017 Barco, Gmr, Portugal

[2] Inst Tecnol Tijuana, Catedras CONACyT Comisionado, Ctr Grad & Invest Quim, Tijuana 22510, BC, Mexico

[3] Univ Santiago de Compostela, Fac Farm, Dept Farm & Tecnol Farmaceut, Santiago De Compostela 15782, Spain

来源：

SMALL | 2015年 / 11卷 / 30期

关键词：

biomaterials; cell encapsulation; drug delivery; hierarchical carriers; superhydrophobic surfaces; HYDROGEL CAPSULES; ALGINATE; DELIVERY; ENCAPSULATION; PARTICLES; RELEASE; MATRIX;

D O I：

10.1002/smll.201500192

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Hierarchical polymeric carriers with high encapsulation efficiencies are fabricated via a biocompatible strategy developed using superhydrophobic (SH) surfaces. The carries are obtained by the incorporation of cell/BSA-loaded dextran-methacrylate (DEXT-MA) microparticles into alginate (ALG) macroscopic beads. Engineered devices like these are expected to boost the development of innovative and customizable systems for biomedical and biotechnological purposes. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：3648 / 3652

页数：5

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