Meshes-to-Fibrils Transition of Gellan Gum Hydrogel Architecture by Thermal Annealing

被引：4

作者：

Abalymov, Anatolii A. ^{[1
,2
]}

Van der Meeren, Louis ^{[1
]}

Van de Walle, Davy ^{[3
]}

Dewettinck, Koen ^{[3
]}

Skirtach, Andre G. ^{[1
]}

Parakhonskiy, Bogdan V. ^{[1
]}

机构：

[1] Univ Ghent, Dept Biotechnol, B-9000 Ghent, Belgium

[2] Saratov NG Chernyshevskii State Univ, Dept Nano & Biomed Technol, Saratov 410012, Russia

[3] Univ Ghent, Dept Food Technol Safety & Hlth, Food Struct & Funct Res Grp, B-9000 Ghent, Belgium

来源：

MACROMOLECULAR MATERIALS AND ENGINEERING | 2020年 / 305卷 / 12期

关键词：

fibrillar hydrogels; gellan gum; thermal annealing; SCAFFOLDS; NANOFIBERS; DESIGN; MINERALIZATION; ORIENTATION; FABRICATION; COATINGS; DELIVERY; FIBERS;

D O I：

10.1002/mame.202000308

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The possibilities created by tuning the architecture of hydrogels open up extensive opportunities for their application in tissue engineering and biomedicine. A simple and effective procedure is developed here, based on thermal annealing, which affects the alignment of the fibrils and results in a mesh-like structure. Atomic force microscopy and cryo-scanning electron microscopy are used to characterize the resultant gel. The alignment angle is demonstrated to take place spontaneously, providing an easy way for self-assembly of such structures. The protocol developed here is likely to be applicable in numerous areas of biomedicine and tissue engineering.

引用

页数：5

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