Detection of the ovarian cancer biomarker CA-125 using chemiluminescence resonance energy transfer to graphene quantum dots

被引：152

作者：

Al-Ogaidi, Israa ^{[1
,2
]}

Gou, Honglei ^{[2
]}

Aguilar, Zoraida P. ^{[3
]}

Guo, Shouwu ^{[4
]}

Melconian, Alice K. ^{[1
]}

Al-Kazaz, Abdul Kareem A. ^{[1
]}

Meng, Fanke ^{[2
]}

Wu, Nianqiang ^{[2
]}

机构：

[1] Univ Baghdad, Dept Biotechnol, Coll Sci, Baghdad, Iraq

[2] W Virginia Univ, Dept Mech & Aerosp Engn, Morgantown, WV 26506 USA

[3] Zystein LLC, Fayetteville, AR 72703 USA

[4] Shanghai Jiao Tong Univ, Key Lab Thin Film & Microfabricat, Minist Educ, Res Inst Micro Nano Sci & Technol, Shanghai 200240, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 11期

基金：

美国国家科学基金会;

关键词：

BIOSENSING PLATFORM; GOLD; NANOPARTICLES; FRET; DNA; CA125; OXIDE;

D O I：

10.1039/c3cc47701k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An immunoassay has been developed for the detection of the ovarian cancer biomarker CA-125 by utilizing the chemiluminescence resonance energy transfer to graphene quantum dots. This biosensor shows a wide linear range from 0.1 U mL(-1) to 600 U mL(-1) with a limit of detection of 0.05 U mL(-1) for CA-125 in a buffer solution.

引用

收藏

页码：1344 / 1346

页数：3

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