Synthesis of some A- and D-ring fused steroidal pyrazoles, isoxazoles and pyrimidines

被引：41
|
作者：
Laitonjam, WS [1 ]
Raikumar, TS [1 ]
Chingakham, BS [1 ]
机构：
[1] Manipur Univ, Dept Chem, Imphal 795003, Manipur, India
来源：
STEROIDS | 2002年 / 67卷 / 3-4期
关键词：
synthesis; fused steroids; pyrazoles; isoxazoles; pyrimidines;
D O I：
10.1016/S0039-128X(01)00146-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The preparation of steroidal heterocycles containing pyrazole, isoxazole and pyrimidine rings fused to the 2,3- and 16,17-positions of the steroid nucleus is described. These were prepared by the reaction of hydrazine, hydroxylamine and guanidine, respectively, with 2-ethoxymethylene-3-oxo- or 16-ethoxymethylene-17-oxo- or 2-bis(methylthio)methylene-3-oxo- or 16-bis(methylthio)methylene-17-oxo-steroids. (C) 2002 Elsevier Science Inc. All rights reserved.
引用
收藏
页码：203 / 209
页数：7
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