Antihypertensive drug prescription pattern before and during pregnancy in France

被引:4
作者
Duhalde, Veronique [1 ]
Delarue, Caroline [1 ]
Lacroix, Isabelle [1 ]
Suarez, Carole [2 ]
Bourrel, Robert [2 ]
Montastruc, Jean-Louis [1 ]
Damase-Michel, Christine [1 ]
机构
[1] Univ Toulouse, Fac Med, Lab Pharmacol Med & Clin, Unite Pharmacoepidemiol,EA 3696, F-31000 Toulouse, France
[2] Caisse Reg Assurance Malad Midi Pyrenees, F-31065 Toulouse 9, France
关键词
Antihypertensive drug; Pregnancy; Women; Foetotoxicity; RECEPTOR ANTAGONISTS; MEDICATION USE; ANGIOTENSIN; HYPERTENSION; EXPOSURE;
D O I
10.1016/j.preghy.2011.01.001
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: This study provides firsthand information on antihypertensive prescriptions before and during pregnancy in France. Methods: The study, on 23,898 women, was carried out using data from the French Health Insurance System. Results: Before and during pregnancy, 1.1% and 5.1% of women received prescriptions for antihypertensive drugs: beta blockers and diuretics before, and nifedipine, nicardipine, labetalol and methyldopa during pregnancy. Sixty-six pregnant women were exposed to angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists. Conclusion: Pregnant women still receive prescriptions for harmful drugs. In order to prevent such exposures, it should be recommended to avoid these prescriptions in women of child-bearing age who plan to be pregnant. (C) 2011 International Society for the Study of Hypertension in Pregnancy. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:185 / 189
页数:5
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