Herpes Simplex Virus Encephalitis: Toll-Free Access to the Brain

被引:9
作者
Leib, David A. [1 ]
机构
[1] Geisel Sch Med Dartmouth, Dept Microbiol & Immunol, Lebanon, NH 03756 USA
关键词
DEFICIENCY; RECEPTOR-3;
D O I
10.1016/j.chom.2012.11.005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Herpes simplex encephalitis (HSE) is a devastating infection of the central nervous system (CNS). Lafaille et al. (2012) show that susceptibility to HSE is due to mutations in Toll-like receptor response pathways that directly reduce the intrinsic resistance of neurons and other cells in the CNS to HSV infection.
引用
收藏
页码:731 / 732
页数:2
相关论文
共 50 条
  • [31] RIPK3 and caspase 8 collaborate to limit herpes simplex encephalitis
    Guo, Hongyan
    Koehler, Heather S.
    Mocarski, Edward S.
    Dix, Richard D.
    PLOS PATHOGENS, 2022, 18 (09)
  • [32] Polymorphisms in Toll-like receptor 3 confer natural resistance to human herpes simplex virus type 2 infection
    Svensson, Alexandra
    Tunback, Petra
    Nordstrom, Inger
    Padyukov, Leonid
    Eriksson, Kristina
    JOURNAL OF GENERAL VIROLOGY, 2012, 93 : 1717 - 1724
  • [33] Herpes simplex encephalitis due to a mutation in an E3 ubiquitin ligase
    Bibert, Stephanie
    Quinodoz, Mathieu
    Perriot, Sylvain
    Krebs, Fanny S.
    Jan, Maxime
    Malta, Rita C.
    Collinet, Emilie
    Canales, Mathieu
    Mathias, Amandine
    Faignart, Nicole
    Roulet-Perez, Eliane
    Meylan, Pascal
    Brouillet, Rene
    Opota, Onya
    Lozano-Calderon, Leyder
    Fellmann, Florence
    Guex, Nicolas
    Zoete, Vincent
    Asner, Sandra
    Rivolta, Carlo
    Du Pasquier, Renaud
    Bochud, Pierre-Yves
    NATURE COMMUNICATIONS, 2024, 15 (01)
  • [34] Encephalitis and poor neuronal death-mediated control of herpes simplex virus in human inherited RIPK3 deficiency
    Liu, Zhiyong
    Reino, Eduardo J. Garcia
    Harschnitz, Oliver
    Guo, Hongyan
    Chan, Yi-Hao
    Khobrekar, Noopur V.
    Hasek, Mary L.
    Dobbs, Kerry
    Rinchai, Darawan
    Materna, Marie
    Matuozzo, Daniela
    Lee, Danyel
    Bastard, Paul
    Chen, Jie
    Lee, Yoon Seung
    Kim, Seong K.
    Zhao, Shuxiang
    Amin, Param
    Lorenzo, Lazaro
    Seeleuthner, Yoann
    Chevalier, Remi
    Mazzolao, Laure
    Gay, Claire
    Stephan, Jean-Louis
    Milisavljevic, Baptiste
    Boucherit, Soraya
    Rozenberg, Flore
    Diego, Rebeca Perez de
    Dix, Richard D.
    Marr, Nico
    Beziat, Vivien
    Cobat, Aurelie
    Aubar, Melodie
    Abel, Laurent
    Chabrier, Stephane
    Smith, Gregory A.
    Notarangelo, Luigi D.
    Mocarski, Edward S.
    Studer, Lorenz
    Casanova, Jean-Laurent
    Zhang, Shen-Ying
    SCIENCE IMMUNOLOGY, 2023, 8 (82)
  • [35] Human TRAF3 Adaptor Molecule Deficiency Leads to Impaired Toll-like Receptor 3 Response and Susceptibility to Herpes Simplex Encephalitis
    de Diego, Rebeca Perez
    Sancho-Shimizu, Vanessa
    Lorenzo, Lazaro
    Puel, Anne
    Plancoulaine, Sabine
    Picard, Capucine
    Herman, Melina
    Cardon, Annabelle
    Durandy, Anne
    Bustamante, Jacinta
    Vallabhapurapu, Sivakumar
    Bravo, Jeronimo
    Warnatz, Klaus
    Chaix, Yves
    Cascarrigny, Francoise
    Lebon, Pierre
    Rozenberg, Flore
    Karin, Michael
    Tardieu, Marc
    Al-Muhsen, Saleh
    Jouanguy, Emmanuelle
    Zhang, Shen-Ying
    Abel, Laurent
    Casanova, Jean-Laurent
    IMMUNITY, 2010, 33 (03) : 400 - 411
  • [36] Virus encephalitis of mixed genesis (cytomegalovirus and simple herpes virus type 1)
    Shavlovskaya, O. A.
    ZHURNAL NEVROLOGII I PSIKHIATRII IMENI S S KORSAKOVA, 2013, 113 (12) : 100 - 104
  • [37] Effects of toll-like receptor 3 on herpes simplex virus type-1-infected mouse neural stem cells
    Sun, Xiuning
    Shi, Lihong
    Zhang, Haoyun
    Li, Ruifang
    Liang, Ruiwen
    Liu, Zhijun
    CANADIAN JOURNAL OF MICROBIOLOGY, 2015, 61 (03) : 201 - 208
  • [38] Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity
    Guo, Yiqi
    Audry, Magali
    Ciancanelli, Michael
    Alsina, Laia
    Azevedo, Joana
    Herman, Melina
    Anguiano, Esperanza
    Sancho-Shimizu, Vanessa
    Lorenzo, Lazaro
    Pauwels, Elodie
    Philippe, Paul Bastard
    de Diego, Rebeca Perez
    Cardon, Annabelle
    Vogt, Guillaume
    Picard, Capucine
    Andrianirina, Zafitsara Zo
    Rozenberg, Flore
    Lebon, Pierre
    Plancoulaine, Sabine
    Tardieu, Marc
    Doireau, Valerie
    Jouanguy, Emmanuelle
    Chaussabel, Damien
    Geissmann, Frederic
    Abel, Laurent
    Casanova, Jean-Laurent
    Zhang, Shen-Ying
    JOURNAL OF EXPERIMENTAL MEDICINE, 2011, 208 (10) : 2083 - 2098
  • [39] Herpes simplex encephalitis in a patient with a distinctive form of inherited IFNAR1 deficiency
    Bastard, Paul
    Manry, Jeremy
    Chen, Jie
    Rosain, Jeremie
    Seeleuthner, Yoann
    AbuZaitun, Omar
    Lorenzo, Lazaro
    Khan, Taushif
    Hasek, Mary
    Hernandez, Nicholas
    Bigio, Benedetta
    Zhang, Peng
    Levy, Romain
    Shrot, Shai
    Reino, Eduardo J. Garcia
    Lee, Yoon-Seung
    Boucherit, Soraya
    Aubart, Melodie
    Gijsbers, Rik
    Beziat, Vivien
    Li, Zhi
    Pellegrini, Sandra
    Rozenberg, Flore
    Marr, Nico
    Meyts, Isabelle
    Boisson, Bertrand
    Cobat, Aurelie
    Bustamante, Jacinta
    Zhang, Qian
    Jouangy, Emmanuelle
    Abel, Laurent
    Somech, Raz
    Casanova, Jean-Laurent
    Zhang, Shen-Ying
    JOURNAL OF CLINICAL INVESTIGATION, 2021, 131 (01)
  • [40] In Vivo Reactivation of Latent Herpes Simplex Virus 1 in Mice Can Occur in the Brain before Occurring in the Trigeminal Ganglion
    Yao, Hui-Wen
    Ling, Pin
    Tung, Yuk-Ying
    Hsu, Sheng-Min
    Chen, Shun-Hua
    JOURNAL OF VIROLOGY, 2014, 88 (19) : 11264 - 11270