Herpes Simplex Virus Encephalitis: Toll-Free Access to the Brain

被引：9
|
作者：
Leib, David A. [1 ]
机构：
[1] Geisel Sch Med Dartmouth, Dept Microbiol & Immunol, Lebanon, NH 03756 USA
来源：
CELL HOST & MICROBE | 2012年 / 12卷 / 06期
关键词：
DEFICIENCY; RECEPTOR-3;
D O I：
10.1016/j.chom.2012.11.005
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Herpes simplex encephalitis (HSE) is a devastating infection of the central nervous system (CNS). Lafaille et al. (2012) show that susceptibility to HSE is due to mutations in Toll-like receptor response pathways that directly reduce the intrinsic resistance of neurons and other cells in the CNS to HSV infection.
引用
收藏
页码：731 / 732
页数：2
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