The Dynamics of HCF-1 Modulation of Herpes Simplex Virus Chromatin during Initiation of Infection

被引:36
作者
Vogel, Jodi L. [1 ]
Kristie, Thomas M. [1 ]
机构
[1] NIAID, NIH, Bethesda, MD 20892 USA
来源
VIRUSES-BASEL | 2013年 / 5卷 / 05期
基金
美国国家卫生研究院;
关键词
herpes simplex virus; chromatin; HCF-1; Setd1A; latency; histone demethylase; HOST-CELL FACTOR; TRANSCRIPTIONAL COACTIVATOR HCF-1; HISTONE ACETYLTRANSFERASE COMPLEX; MECHANISM-BASED INACTIVATOR; IMMEDIATE-EARLY PROMOTERS; LYTIC INFECTION; GENE-EXPRESSION; O-GLCNAC; FACTOR-I; METHYLTRANSFERASE MLL1;
D O I
10.3390/v5051272
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Successful infection of herpes simplex virus is dependent upon chromatin modulation by the cellular coactivator host cell factor-1 (HCF-1). This review focuses on the multiple chromatin modulation components associated with HCF-1 and the chromatin-related dynamics mediated by this coactivator that lead to the initiation of herpes simplex virus (HSV) immediate early gene expression.
引用
收藏
页码:1272 / 1291
页数:20
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