Effects of verapamil combinations with enalapril or indapamide on plasma, vascular and platelet hemostasis and biochemical markers of endothelial dysfunction in patients with arterial hypertension and metabolic syndrome

被引：0

作者：

Krasnova, N. M. ^{[1
]}

Kalashnikova, T. P. ^{[1
]}

Vengerovsky, A. I. ^{[1
]}

Idrisova, E. M. ^{[1
]}

Kulagina, I. V. ^{[1
]}

Suslova, T. E. ^{[1
]}

Gruzdeva, O. V. ^{[1
]}

Kremeno, S. V. ^{[1
]}

机构：

[1] Siberian State Med Univ, Fed Agcy Hlth Care & Social Dev, Tomsk, Russia

来源：

RUSSIAN JOURNAL OF CARDIOLOGY | 2008年 / 03期

关键词：

Metabolic syndrome; arterial hypertension; platelet aggregation; Willebrand factor; NO2; verapamil; enalapril; indapamide;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The combination of verapamil retard and enalapril, or verapamil retard and indapamide SR similarly and significantly increased high-density lipoprotein cholesterol and stable NO2 metabolite levels, reducing platelet aggregation in patients with metabolic syndrome (MS). Compared to the combination of verapamil retard and indapamide SR, the combination of verapamil retard and enalapril significantly reduced atherogenicity coefficient, glycated hemoglobin, glucose and soluble fibrin-monomer complex levels, increasing nitrite concentration and activating plasminogen.

引用

页码：49 / 54

页数：6

共 12 条

[1]

MARTYNOV AI, 2004, KARDIOVASK TERAPIYA, V3, P20

[2]

MEDVEDEV IN, 2004, FARMATEKA, V138, P58

[3]

MYCHKA VB, 2007, CONSILIUM MEDICUM, V8, P66

[4]

NEBIERIDZE DV, 2006, RUSS MED ZH, V14, P3

[5]

NEDOGODA SV, 2006, SERDTSE, V4, P21

[6] A calcium antagonist vs a non-calcium antagonist hypertension treatment strategy for patients with coronary artery disease - The International Verapamil-Trandolapril Study (INVEST): A randomized controlled trial [J].

Pepine, CJ ;

Handberg, EM ;

Cooper-Dehoff, RM ;

Marks, RG ;

Kowey, P ;

Messerli, FH ;

Mancia, G ;

Cangiano, JL ;

Garcia-Barreto, D ;

Keltai, M ;

Erdine, S ;

Bristol, HA ;

Kolb, HR ;

Bakris, GL ;

Cohen, JD ;

Parmley, WW .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 290 (21) :2805-2816

[7]

Ripp TM, 2007, KARDIOLOGIYA, V47, P45

[8]

VOROBYOVA YN, 2006, SIB MED ZH, V21, P78

[9]

VOSKOBOY IV, 2001, KLINICHESKAYA MEDITS, P19

[10]

ZADIOCHENKO VS, 2004, CONSILIUM MEDICUM, V6, P63

← 1 2 →