Calcium-Alkali Syndrome in the Modern Era

被引:30
作者
Patel, Ami M. [1 ]
Adeseun, Gbemisola A. [2 ]
Goldfarb, Stanley [3 ]
机构
[1] Drexel Univ, Div Nephrol & Hypertens, Coll Med, Philadelphia, PA 19102 USA
[2] Univ So Calif, Keck Sch Med, Div Nephrol, Los Angeles, CA 90033 USA
[3] Univ Penn, Div Renal Electrolyte & Hypertens, Perelman Sch Med, Philadelphia, PA 19104 USA
关键词
calcium-alkali syndrome; milk-alkali syndrome; hypercalcemia; VITAMIN-D; MYOCARDIAL-INFARCTION; D SUPPLEMENTATION; SENSING RECEPTOR; SERUM-CALCIUM; RISK; DISEASE; HEALTH; COHORT; HYPERCALCEMIA;
D O I
10.3390/nu5124880
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The ingestion of calcium, along with alkali, results in a well-described triad of hypercalcemia, metabolic alkalosis, and renal insufficiency. Over time, the epidemiology and root cause of the syndrome have shifted, such that the disorder, originally called the milk-alkali syndrome, is now better described as the calcium-alkali syndrome. The calcium-alkali syndrome is an important cause of morbidity that may be on the rise, an unintended consequence of shifts in calcium and vitamin D intake in segments of the population. We review the pathophysiology of the calcium-alkali syndrome.
引用
收藏
页码:4880 / 4893
页数:14
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