Susceptibility of Staphylococcus spp. Isolated from Milk of Goats with Mastitis to Antibiotics and Green Propolis Extracts

被引：0
|
作者：
Santos Neto, T. M. [2 ]
Mota, R. A. [2 ]
Silva, L. B. G. [2 ]
Viana, D. A. [3 ]
Lima-Filho, J. L. [4 ]
Sarubbo, L. A. [5 ]
Converti, A. [6 ]
Porto, A. L. F. [1 ]
机构：
[1] Univ Fed Rural Pernambuco, Dept Anim Morphol & Physiol, BR-52171900 Dois Irmaos, PE, Brazil
[2] Univ Fed Rural Pernambuco, Dept Vet Med, BR-52171900 Dois Irmaos, PE, Brazil
[3] Univ Fed Pernambuco, Biotechnol Lab LIKA, Recife, PE, Brazil
[4] Univ Fed Pernambuco, Dept Biochem, Recife, PE, Brazil
[5] Univ Catolica Pernambuco, Inst Res Environm Sci, Ctr Sci & Technol, Recife, PE, Brazil
[6] Univ Genoa, Dept Chem & Proc Engn, Genoa, Italy
来源：
LETTERS IN DRUG DESIGN & DISCOVERY | 2009年 / 6卷 / 01期
关键词：
Antimicrobial activity; Goat milk; Mastitis; Green propolis; Staphylococcus spp; ANTIBACTERIAL ACTIVITY; PREVALENCE;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The antimicrobial activity of ethanolic and aqueous extracts of a commercial green propolis and of 13 standard antibiotics was evaluated against Staphylococcus spp. strains isolated from milk of goats with mastitis. More than 95% of the isolates were sensitive to cephalothin and tetracycline, whereas only 28.9% were sensitive to streptomycin. All the isolates were susceptible to both ethanolic and aqueous extracts, but the former showed the higher antimicrobial activity. The larger mean diameter of the inhibition zone of coagulase-negative staphylococci (15.5 mm) was in fact obtained with the ethanolic extract. A Minimum Inhibitory Concentration of 50 mu g/mL of both extracts was determined, which highlighted a promoting in vitro activity.
引用
收藏
页码：63 / 68
页数：6
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