Vibrational spectroscopic analysis of theophylline in a pharmaceutical granulation process using near-, mid- and far-infrared/terahertz spectroscopy

被引：0

作者：

Sakamoto, Tomoaki ^{[1
]}

Sasaki, Tetsuo

Nishizawa, Jun-ichi

Katori, Noriko ^{[1
]}

Hiyama, Yukio ^{[1
]}

Okuda, Haruhiro ^{[1
]}

机构：

[1] Natl Inst Hlth Sci, Div Drugs, Tokyo 1588501, Japan

来源：

2012 37TH INTERNATIONAL CONFERENCE ON INFRARED, MILLIMETER, AND TERAHERTZ WAVES (IRMMW-THZ) | 2012年

关键词：

TERAHERTZ WAVE GENERATION; REGION; GAP;

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Vibrational spectroscopic analysis of theophylline in a wet granulation process was performed. An anhydride was converted to a monohydrate during the granulation and a dehydration of monohydrate progressed during the drying process. A C-N stretching would be affected by an interaction between theophylline and a binder under a wet granulation process.

引用

页数：2