One-pot fluorination and asymmetric Michael addition promoted by recyclable fluorous organocatalysts

被引：25
作者：
Yi, Wen-Bin [1 ]
Zhang, Zijuan [2 ]
Huang, Xin [2 ]
Tanner, Angela [2 ]
Cai, Chun [1 ]
Zhang, Wei [2 ]
机构：
[1] Nanjing Univ Sci & Technol, Sch Chem Engn, Nanjing 210094, Jiangsu, Peoples R China
[2] Univ Massachusetts, Dept Chem, Boston, MA 02125 USA
来源：
RSC ADVANCES | 2013年 / 3卷 / 40期
基金：
中国国家自然科学基金;
关键词：
ENANTIOSELECTIVE CONJUGATE ADDITION; DIELS-ALDER REACTIONS; NITROALKENES; CHALCONES; CARBONYL; MALONATE; KETONES; UREA;
D O I：
10.1039/c3ra42501k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel one-pot fluorination and asymmetric Michael addition reaction sequence promoted by recyclable fluorous bifunctional cinchona alkaloid-thiourea organocatalysts is introduced for the synthesis of alpha-fluoro-beta-ketoesters bearing two chiral centers.
引用
收藏
页码：18267 / 18270
页数：4
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