Unilateral testicular torsion: Protective effect of verapamil on contralateral testicular histology

被引:20
作者
Sarica, K [1 ]
Bakir, K [1 ]
Yagci, F [1 ]
Erbagci, A [1 ]
Topcu, O [1 ]
Uysal, O [1 ]
机构
[1] Univ Gaziantep, Sahinbey Hosp, Dept Urol, Sch Med, TR-27070 Kolejtepe Gaziantep, Turkey
关键词
testicular torsion; tubular diameter; verapamil; histology;
D O I
10.1159/000030382
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
In this experimental study, it was our aim to reduce the effects of ischemic insults to the contralateral testicle after unilateral testicular torsion. The protective effect of a calcium channel blocking agent (verapamil) on the histology and the tubular diameter of contralateral testicle was evaluated, Following a definite period of unilateral testicular torsion (i.e., 4 h), the protective effect of this specific medication was evaluated both after detorsion and orchiectomy procedures, The results of our study demonstrated the protective effect of verapamil on both parameters, especially in animals undergoing orchiectomy. The majority of the specimens demonstrated normal histologic findings together with preserved tubular structures after a 1-week period under verapamil medication.
引用
收藏
页码:159 / 163
页数:5
相关论文
共 50 条
  • [31] Protective effect of urapidil on testicular torsion-detorsion injury in rats
    Mestrovic, Jakov
    Pogorelic, Zenon
    Drmic-Hofman, Irena
    Vilovic, Katarina
    Todoric, Davor
    Popovic, Marijana
    SURGERY TODAY, 2017, 47 (03) : 393 - 398
  • [32] Mannitol has a protective effect on testicular torsion: An experimental rat model
    Kurt, Omer
    Yazici, Cenk Murat
    Erboga, Mustafa
    Turan, Cuneyt
    Bozdemir, Yeliz
    Akbas, Alpaslan
    Turker, Polat
    Aktas, Cevat
    Aydin, Murat
    Yesildag, Ebru
    JOURNAL OF PEDIATRIC UROLOGY, 2016, 12 (03) : 167.e1 - 167.e8
  • [33] The protective effect of erythropoietin infusion on testicular torsion/detorsion: an experimental study
    Burhan Köseoğlu
    Engin Yılmaz
    Kadir Ceylan
    Ersan Uzun
    İrfan Bayram
    Fatih Hızlı
    International Urology and Nephrology, 2009, 41 : 85 - 91
  • [34] Effect of Pediatric Testicular Torsion on Testicular Function in the Short Term
    Taskinen, Seppo
    Makela, Eija
    Raivio, Taneli
    JOURNAL OF PEDIATRIC SURGERY, 2020, 55 (08) : 1613 - 1615
  • [35] The Effect of Testicular Torsion Duration on Testicular Steroidogenesis in the Rat Model
    Kurt, Omer
    Yazici, Cenk Murat
    Gevher, Fetullah
    Balci, Huriye
    Yitik, Ali
    Ozkara, Hamdi
    UROLOGIA INTERNATIONALIS, 2016, 97 (03) : 358 - 364
  • [36] Case Report: Testicular Torsion in Unilateral Supernumerary Testis
    Lu Xiaofei
    Zhou Benzhang
    FRONTIERS IN PEDIATRICS, 2022, 10
  • [37] Effect of tunica albuginea incision on testicular tissue in testicular torsion
    Sahin, Ahmet Hikmet
    Cevizci, Mehmet Nuri
    Turan, Guelay
    Sahin, Hatice
    ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, 2022, 28 (10): : 1367 - 1372
  • [38] Treatment of contralateral hydrocele in neonatal testicular torsion: Is less more?
    Kaefer, Martin
    Agarwal, Deepak
    Misseri, Rosalia
    Whittam, Benjamin
    Hubert, Katherine
    Szymanski, Konrad
    Rink, Richard
    Cain, Mark P.
    JOURNAL OF PEDIATRIC UROLOGY, 2016, 12 (05) : 306.e1 - 306.e4
  • [39] Protective role of natural antioxidant supplementation on testicular tissue after testicular torsion and detorsion
    Ünsal, A
    Eroglu, M
    Avci, A
    Cimentepe, E
    Guven, C
    Balbay, MD
    Durak, I
    SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY, 2006, 40 (01): : 17 - 22
  • [40] Unilateral testicular torsion:: Evaluation of bcl-2, p-53 and PCNA expression in contralateral testes
    Sarica, K
    Bakir, K
    Erbagci, A
    Yagci, F
    Uysal, O
    Uçak, R
    UROLOGIA INTERNATIONALIS, 2001, 66 (02) : 94 - 99