Unilateral testicular torsion: Protective effect of verapamil on contralateral testicular histology

被引:20
|
作者
Sarica, K [1 ]
Bakir, K [1 ]
Yagci, F [1 ]
Erbagci, A [1 ]
Topcu, O [1 ]
Uysal, O [1 ]
机构
[1] Univ Gaziantep, Sahinbey Hosp, Dept Urol, Sch Med, TR-27070 Kolejtepe Gaziantep, Turkey
关键词
testicular torsion; tubular diameter; verapamil; histology;
D O I
10.1159/000030382
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
In this experimental study, it was our aim to reduce the effects of ischemic insults to the contralateral testicle after unilateral testicular torsion. The protective effect of a calcium channel blocking agent (verapamil) on the histology and the tubular diameter of contralateral testicle was evaluated, Following a definite period of unilateral testicular torsion (i.e., 4 h), the protective effect of this specific medication was evaluated both after detorsion and orchiectomy procedures, The results of our study demonstrated the protective effect of verapamil on both parameters, especially in animals undergoing orchiectomy. The majority of the specimens demonstrated normal histologic findings together with preserved tubular structures after a 1-week period under verapamil medication.
引用
收藏
页码:159 / 163
页数:5
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