CTACl AS CATALYST FOR FOUR-COMPONENT, ONE-POT SYNTHESIS OF PYRANOPYRAZOLE DERIVATIVES IN AQUEOUS MEDIUM

被引：89
|
作者：
Wu, Mingshu [1 ]
Feng, Qinqin [2 ]
Wan, Dehui [1 ]
Ma, Jinya [1 ]
机构：
[1] Hainan Normal Univ, Coll Chem & Chem Engn, Haikou 571158, Peoples R China
[2] Anyang Normal Univ, Coll Chem & Chem Engn, Anyang, Henan, Peoples R China
来源：
SYNTHETIC COMMUNICATIONS | 2013年 / 43卷 / 12期
基金：
中国国家自然科学基金;
关键词：
CTACl catalysis; four-component reaction; pyrano[2; 3-c]pyrazole derivatives; water medium; MULTICOMPONENT REACTIONS; IDENTIFICATION; HETEROCYCLES; NITRILES; WATER;
D O I：
10.1080/00397911.2012.666315
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An environmentally benign four-component reaction in aqueous medium in the presence of cetyltrimethylammonium chloride (CTACl) has been developed for the synthesis of 6-amino-3-methyl-4-aryl-/1-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile. The method presented is mild, environmentally friendly, inexpensive, and functionality tolerant and gives the products in good to excellent yields.
引用
收藏
页码：1721 / 1726
页数：6
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