Palladium-Catalyzed Decarboxylative Arylation of Benzoylacrylic Acids toward the Synthesis of Chalcones

被引：33
作者：
Unoh, Yuto [1 ]
Hirano, Koji [1 ]
Satoh, Tetsuya [1 ,2 ]
Miura, Masahiro [1 ]
机构：
[1] Osaka Univ, Fac Engn, Dept Appl Chem, Suita, Osaka 5650871, Japan
[2] ACT C, JST, Kawaguchi, Saitama 3320012, Japan
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 78卷 / 10期
关键词：
CARBOXYLIC-ACIDS; COUPLING REACTIONS; ARYLBORONIC ACIDS; C-H; FLUORESCENCE;
D O I：
10.1021/jo400716e
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
It has been found that readily available 3-benzoylacrylic acids undergo palladium-catalyzed decarboxylative arylation with arylboronic acids in the presence of a copper salt oxidant to produce chalcone derivatives. The decarboxylative arylation could also be achieved using aryl halides as the alternative aryl source to expand the applicable scope.
引用
收藏
页码：5096 / 5102
页数：7
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