EURRECA-Estimating Selenium Requirements for Deriving Dietary Reference Values

被引：81

作者：

Hurst, Rachel ^{[1
]}

Collings, Rachel ^{[1
]}

Harvey, Linda J. ^{[1
]}

King, Maria ^{[1
]}

Hooper, Lee ^{[1
]}

Bouwman, Jildau ^{[2
]}

Gurinovic, Mirjana ^{[3
]}

Fairweather-Tait, Susan J. ^{[1
]}

机构：

[1] Univ E Anglia, Dept Nutr, Norwich Med Sch, Norwich NR4 7TJ, Norfolk, England

[2] TNO, NL-3700 AJ Zeist, Netherlands

[3] Univ Belgrade, Inst Med Res, Ctr Res Excellence Nutr & Metab, Belgrade 11000, Serbia

来源：

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION | 2013年 / 53卷 / 10期

基金：

英国生物技术与生命科学研究理事会;

关键词：

Selenium; nutrition; dietary reference values; selenoprotein P; glutathione peroxidase; plasma selenium; serum selenium; requirements; GLUTATHIONE-PEROXIDASE ACTIVITY; FOOD-FREQUENCY QUESTIONNAIRE; SINGLE-NUCLEOTIDE POLYMORPHISMS; MANGANESE SUPEROXIDE-DISMUTASE; HUMAN-IMMUNODEFICIENCY-VIRUS; ANTIOXIDANT DEFENSE SYSTEM; HIV-INFECTED INDIVIDUALS; PROSTATE-CANCER RISK; SELENOPROTEIN-P; MICRONUTRIENT SUPPLEMENTATION;

D O I：

10.1080/10408398.2012.742861

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Current reference values for selenium, an essential micronutrient, are based on the intake of selenium that is required to achieve maximal glutathione peroxidase activity in plasma or erythrocytes. In order to assess the evidence of relevance to setting dietary reference values for selenium, the EURRECA Network of Excellence focused on systematic searches, review, and evaluation of (i) selenium status biomarkers and evidence for relationships between intake and status biomarkers, (ii) selenium and health (including the effect of intake and/or status biomarkers on cancer risk, immune function, HIV, cognition, and fertility), (iii) bioavailability of selenium from the diet, and (iv) impact of genotype/single nucleotide polymorphisms on status or health outcomes associated with selenium. The main research outputs for selenium and future research priorities are discussed further in this review.

引用

页码：1077 / 1096

页数：20

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