Objective: To evaluate single center results of the Zenith stent-graft for elective abdominal aortic aneurysm repair. Methods: Data from all patients treated with a Zenith graft between March 1999 and December 2006 were retrospectively analyzed from a prospective database. Outcome measures were technical success, all-cause and aneurysm related mortality, late complications, and re-interventions. Results: A total of 234 patients were included, of which 216 were mate. Mean age was 72.1 +/- 6.9 years. Mean diameter of the aneurysm was 60.9 +/- 10 mm. Technical success rate was 98.3%. Thirty day mortality was 1.7%. Median follow-up was 26.9 months (range, 1-104). Overall survival was 92.2 +/- 1.8% at 1 year, 87.2 +/- 2.3% at 2 years, and 69.9 +/- 4.6% at 5 years. During follow-up, one aneurysm ruptured due to limb disconnection, which was treated by bridging stent-grafting. Re-interventions were performed in 9.2% of the patients, with 79% by endovascular means. There was no mortality related to re-intervention. Conclusions: Endovascular abdominal aortic aneurysm repair with the Zenith device provides excellent results with a low risk for aneurysm-related death and rupture, and a low re-intervention rate in the mid-term. (C) 2008 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.