A ratiometric fluorescent probe for magnesium employing excited state intramolecular proton transfer

被引：108

作者：

Singh, Narinder ^{[1
]}

Kaur, Navneet ^{[1
]}

Mulrooney, Ray C. ^{[1
]}

Callan, John F. ^{[1
]}

机构：

[1] Robert Gordon Univ, Sch Pharm & Life Sci, Aberdeen AB10 1FR, Scotland

来源：

TETRAHEDRON LETTERS | 2008年 / 49卷 / 47期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/j.tetlet.2008.09.052

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple fluorescent sensor has been developed for the ratiometric recognition of Mg2+ in semi-aqueous solution at pH 7.0. The sensor, a Schiff base, undergoes Excited State Intramolecular Proton Transfer (ESIPT) to generate a keto tautomer with proficient Mg2+ binding capability. The sensor displays good selectivity over other metal ions including alkali/alkali earth ions and can measure Mg2+ ion concentration between 2.0 and 30.0 mu M. The binding stoichiometry was established as 2:1 (host:guest) with an association constant (K-21) of (1.4 +/- 0.1) x 10(4) m(-2). The sensor could potentially be used to detect conditions such as hypermagnesaemia. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：6690 / 6692

页数：3

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