Concise Review: Production of Cultured Red Blood Cells from Stem Cells

被引：26
作者：
Bouhassira, Eric E. [1 ,2 ]
机构：
[1] Albert Einstein Coll Med, Dept Cell Biol, Einstein Pluripotent Stem Cell Ctr, Bronx, NY 10461 USA
[2] Albert Einstein Coll Med, Dept Med, Einstein Pluripotent Stem Cell Ctr, Bronx, NY 10461 USA
来源：
STEM CELLS TRANSLATIONAL MEDICINE | 2012年 / 1卷 / 12期
关键词：
Erythropoiesis; Embryonic stem cells; Adult stem cells; Stem/progenitor cell; HUMAN EMBRYONIC STEM; HUMAN ERYTHROID-CELLS; COLONY-FORMING CELLS; EX-VIVO GENERATION; HEMATOPOIETIC STEM; CORD BLOOD; C-MYC; IN-VITRO; YOLK-SAC; ERYTHROLEUKEMIA-CELLS;
D O I：
10.5966/sctm.2012-0097
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
In the Western world, the volunteer-based collection system covers most transfusion needs, but transient shortages regularly develop and blood supplies are vulnerable to potentially major disruptions. The production of cultured red blood cells from stem cells is slowly emerging as a potential alternative. The various cell sources, the niche applications most likely to reach the clinic first, and some of the remaining technical issues are reviewed here. STEM CELLS TRANSLATIONAL MEDICINE 2012;1:927-933
引用
收藏
页码：927 / 933
页数：7
相关论文
共 86 条
[1]  
Adams RJ, 2005, NEW ENGL J MED, V353, P2769
[2]   Prevention of a first stroke by transfusions in children with sickle, cell anemia and abnormal results on transcranial Doppler ultrasonography [J].
Adams, RJ ;
McKie, VC ;
Hsu, L ;
Files, B ;
Vichinsky, E ;
Pegelow, C ;
Abboud, M ;
Gallagher, D ;
Kutlar, A ;
Nichols, FT ;
Bonds, DR ;
Brambilla, D ;
Woods, G ;
Olivieri, N ;
Driscoll, C ;
Miller, S ;
Wang, W ;
Hurlett, A ;
Scher, C ;
Berman, B ;
Carl, E ;
Jones, AM ;
Roach, ES ;
Wright, E ;
Zimmerman, RA ;
Waclawiw, M ;
Pearson, H ;
Powars, D ;
Younkin, D ;
El-Gammal, T ;
Seibert, J ;
Moye, L ;
Espeland, M ;
Murray, R ;
McKinley, R ;
McKinley, S ;
Hagner, S ;
Weiner, S ;
Estow, S ;
Yelle, M ;
Brock, K ;
Carter, E ;
Chiarucci, K ;
Debarr, M ;
Feron, P ;
Harris, S ;
Hoey, L ;
Jacques, K ;
Kuisel, L ;
Lewis, N .
NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (01) :5-11
[3]   The aging population poses a global challenge for blood services [J].
Ali, Akif ;
Auvinen, Marja-Kaisa ;
Rautonen, Jukka .
TRANSFUSION, 2010, 50 (03) :584-588
[4]   PU.1 determines the self-renewal capacity of erythroid progenitor cells [J].
Back, J ;
Dierich, A ;
Bronn, C ;
Kastner, P ;
Chan, S .
BLOOD, 2004, 103 (10) :3615-3623
[5]   Placental umbilical cord whole blood transfusion: a safe and genuine blood substitute for patients of the under-resourced world at emergency [J].
Bhattacharya, N .
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2005, 200 (04) :557-563
[6]   ALLOGENEIC CORD BLOOD RED CELLS FOR TRANSFUSION [J].
Bianchi, Maria ;
Landini, Alessandra ;
Giannatonio, Carmen ;
Papacci, Patrizia ;
d'Onofrio, Giuseppe ;
Zini, Gina .
TRANSFUSION MEDICINE REVIEWS, 2012, 26 (01) :90-91
[7]   Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells [J].
Boitano, Anthony E. ;
Wang, Jian ;
Romeo, Russell ;
Bouchez, Laure C. ;
Parker, Albert E. ;
Sutton, Sue E. ;
Walker, John R. ;
Flaveny, Colin A. ;
Perdew, Gary H. ;
Denison, Michael S. ;
Schultz, Peter G. ;
Cooke, Michael P. .
SCIENCE, 2010, 329 (5997) :1345-1348
[8]   INTERACTION OF 2,3-DIPHOSPHOGLYCERATE WITH VARIOUS HUMAN HEMOGLOBINS [J].
BUNN, HF ;
BRIEHL, RW .
JOURNAL OF CLINICAL INVESTIGATION, 1970, 49 (06) :1088-&
[9]   Directed differentiation and mass cultivation of pure erythroid progenitors from mouse embryonic stem cells [J].
Carotta, S ;
Pilat, S ;
Mairhofer, A ;
Schmidt, U ;
Dolznig, H ;
Steinlein, P ;
Beug, H .
BLOOD, 2004, 104 (06) :1873-1880
[10]   Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells [J].
Chadwick, K ;
Wang, LS ;
Li, L ;
Menendez, P ;
Murdoch, B ;
Rouleau, A ;
Bhatia, M .
BLOOD, 2003, 102 (03) :906-915
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