Secondary and Tertiary Hyperparathyroidism

被引：64

作者：

Jamal, Sophie A. ^{[1
]}

Miller, Paul D. ^{[2
]}

机构：

[1] Univ Toronto, Womens Coll Res Inst, Toronto, ON M5G 1N8, Canada

[2] Colorado Ctr Bone Res, Lakewood, CO USA

来源：

JOURNAL OF CLINICAL DENSITOMETRY | 2013年 / 16卷 / 01期

关键词：

Chronic kidney disease; hyperparathyroidism; serum calcium; RENAL-TRANSPLANT RECIPIENTS; HIGH PHOSPHATE THERAPY; CHRONIC KIDNEY-DISEASE; PERSISTENT HYPERPARATHYROIDISM; VITAMIN-D; HYPOPHOSPHATEMIC RICKETS; ONCOGENIC OSTEOMALACIA; GENE-EXPRESSION; CINACALCET; HORMONE;

D O I：

10.1016/j.jocd.2012.11.012

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We reviewed the etiology and management of secondary and tertiary hyperparathyroidism. Secondary hyperparathyroidism is characterized by an increase-in parathyroid hormone (PTH) that is appropriate and in response to a stimulus, most commonly low serum calcium. In secondary hyperparathyroidism, the serum calcium is normal and the PTH level is elevated. Tertiary hyperparathyroidism is characterized by excessive secretion of PTH after longstanding secondary hyperparathyroidism, in which hypercalcemia has ensued. Tertiary hyperparathyroidism typically occurs in men and women with chronic kidney disease usually after kidney transplant. The etiology and treatment of secondary hyperparathyroidism is relatively straightforward whereas data on the management of tertiary hyperparathyroidism is limited to a few small trials with short follow-up.

引用

页码：64 / 68

页数：5

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