Assessment of BNP and NT-proBNP in emergency department patients presenting with suspected acute coronary syndromes

被引：17

作者：

Cameron, SJ

Green, GB

White, CN

Laterza, OF

Clarke, W

Kim, H

Sokoll, LJ

机构：

[1] Johns Hopkins Med Inst, Dept Pathol, Div Clin Chem, Baltimore, MD 21287 USA

[2] Johns Hopkins Med Inst, Dept Emergency Med, Baltimore, MD 21287 USA

来源：

CLINICAL BIOCHEMISTRY | 2006年 / 39卷 / 01期

关键词：

D O I：

10.1016/j.clinbiochem.2005.10.011

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Objectives: The relationship between BNP and NT-proBNP among physiologically and clinically relevant demographic subgroups has never been clarified in the context of the emergency department (ED). Design and methods: A blood sample taken from patients presenting to the E.D. with suspected acute coronary syndromes (ACS) was analyzed for BNP and NT-proBNP, and correlation between them was examined as an entire group then as subgroups according to gender, ethnicity, age, and comorbidity variables. Results: BNP and NT-proBNP correlate well (0.89, P < 0.0001) in a population of 420 patients and in patient subgroups with a history of various etiologies, including vascular disorders. Conclusions: In general, BNP and NT-proBNP correlate very well in patients with suspected ACS and may aid in the risk stratification process in emergency departments. (c) 2005 The Canadian Society of Clinical Chemists. All rights reserved.

引用

页码：11 / 18

页数：8

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