Comparative evaluation of bioactive compounds of various cultivars of pomegranate (Punica granatum) in different world regions

Pomegranates (Punica granatum) are a significant source of bioactive compounds and have been widely used in traditional Eastern medicine in different countries and cultures. Pomegranate peel and pulp have significantly antioxidant capacity, and pomegranate pulp contain markedly anti-atherogenic activity against atherosclerosis diseases in humans and mice model investigations. Pomegranates from different cultivars possess different bioactive molecules, increasing the desired antioxidant properties genes and chemical profiles. This study provides an overview of geographic origins and an evaluation of the chemical analysis of flavonoids and polyphenolic content of the pomegranate from the local (Persian) and foreign pomegranate cultivars. The present narrative review aims to compare chemical analysis of total phenolic and flavonoids content of different pomegranate cultivars grown in various geographic regions in the world. This review demonstrated that remarkable differences existed in all factors rates measured in various cultivars, being considerably related to many factors such as cultivar type, growing region, maturity, cultivation, climate, edaphic condition, and storage situation. The data would be useful to produce better crops with high nutritional quality.