NATURAL PRODUCTS Emulation illuminates biosynthesis

被引：5
作者：
Mercer, Jaron A. M. [1 ]
Burns, Noah Z. [1 ]
机构：
[1] Stanford Univ, Dept Chem, Stanford, CA 94305 USA
来源：
NATURE CHEMISTRY | 2015年 / 7卷 / 11期
关键词：
EPICOLACTONE;
D O I：
10.1038/nchem.2377
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A concise synthesis of the fungal natural product epicolactone suggests that this highly stereochemically complex yet racemic natural product may come from a cascade reaction between two polyhydroxylated arenes.
引用
收藏
页码：860 / 861
页数：2
相关论文
共 10 条
  • [1] A fresh look at natural tropolonoids
    Bentley, Ronald
    [J]. NATURAL PRODUCT REPORTS, 2008, 25 (01) : 118 - 138
  • [2] TOTAL SYNTHESIS OF CARPANONE
    CHAPMAN, OL
    ENGEL, MR
    SPRINGER, JP
    CLARDY, JC
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1971, 93 (24) : 6696 - &
  • [3] Epicolactone - Natural Product Isolated from the Sugarcane Endophytic Fungus Epicoccum nigrum
    da Silva Araujo, Francisca Diana
    de Lima Favaro, Leia Cecilia
    Araujo, Welington Luiz
    de Oliveira, Fabio Lazzarotto
    Aparicio, Ricardo
    Marsaioli, Anita Jocelyne
    [J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2012, 2012 (27) : 5225 - 5230
  • [4] Ellerbrock P, 2015, NAT CHEM, V7, P879, DOI [10.1038/NCHEM.2336, 10.1038/nchem.2336]
  • [5] Biomimetic Synthesis of the Calcineurin Phosphatase Inhibitor Dibefurin
    Ellerbrock, Pascal
    Armanino, Nicolas
    Trauner, Dirk
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 53 (49) : 13414 - 13418
  • [6] JOHNSON WS, 1991, TETRAHEDRON, V47, pR11
  • [7] THE ENDIANDRIC ACID CASCADE - ELECTROCYCLIZATIONS IN ORGANIC-SYNTHESIS .3. BIOMIMETIC APPROACH TO ENDIANDRIC ACIDS-A-ACID-G - SYNTHESIS OF PRECURSORS
    NICOLAOU, KC
    ZIPKIN, RE
    PETASIS, NA
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1982, 104 (20) : 5558 - 5560
  • [8] Razzak M, 2011, NAT CHEM BIOL, V7, P865, DOI [10.1038/NCHEMBIO.709, 10.1038/nchembio.709]
  • [9] Epicoccolides: Antimicrobial and Antifungal Polyketides from an Endophytic Fungus Epicoccum sp Associated with Theobroma cacao
    Talontsi, Ferdinand Mouafo
    Dittrich, Birger
    Schueffler, Anja
    Sun, Han
    Laatsch, Hartmut
    [J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2013, 2013 (15) : 3174 - 3180
  • [10] Pattern recognition in retrosynthetic analysis: Snapshots in total synthesis
    Wilson, Rebecca M.
    Danishefsky, Samuel J.
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2007, 72 (12) : 4293 - 4305
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