A ratiometric fluorescent sensor with a large Stokes shift for imaging zinc ions in living cells

被引：175

作者：

Xue, Lin ^{[1
,3
]}

Liu, Chun ^{[2
]}

Jiang, Hua ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Chem, CAS Key Lab Photochem, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China

[2] Dalian Univ Technol, Dept Chem Engn, State Key Lab Fine Chem, Dalian 116012, Peoples R China

[3] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 09期

关键词：

BIOLOGICAL APPLICATIONS; INTRACELLULAR ZINC; CHARGE-TRANSFER; PROBE; ZN2+; DESIGN; CHEMOSENSORS; MICROSCOPY; COUMARIN; PLATFORM;

D O I：

10.1039/b814501f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The ratiometric fluorescent sensor FQ1 based on furoquinoline has been designed and synthesized, and not only exhibits a large Stokes shift of 199 nm in a mixture of C2H5OH-H2O (v/v = 8 : 2, 10 mM Tris-HCl, pH = 7.3), but can selectively detect zinc ions in the presence of competing metal ions with a red-shift of 75 nm; moreover, cell stain experiments show that FQ1 can readily reveal a change in intracellular Zn2+.

引用

页码：1061 / 1063

页数：3

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