Polydopamine free radical scavengers

被引：240

作者：

Hu, Junfei ^{[1
]}

Yang, Lei ^{[1
]}

Yang, Peng ^{[1
]}

Jiang, Shaohua ^{[2
]}

Liu, Xianhu ^{[3
]}

Li, Yiwen ^{[1
]}

机构：

[1] Sichuan Univ, Coll Polymer Sci & Engn, State Key Lab Polymer Mat Engn, Chengdu 610065, Peoples R China

[2] Nanjing Forestry Univ, Coll Mat Sci & Engn, Coinnovat Ctr Efficient Proc & Utilizat Forest Re, Nanjing 210037, Peoples R China

[3] Zhengzhou Univ, Natl Engn Res Ctr Adv Polymer Proc Technol, Zhengzhou 450002, Peoples R China

来源：

BIOMATERIALS SCIENCE | 2020年 / 8卷 / 18期

基金：

中国国家自然科学基金;

关键词：

IRON-OXIDE NANOPARTICLES; MELANIN NANOPARTICLES; OXIDATIVE STRESS; REACTIVE OXYGEN; BILIRUBIN NANOPARTICLES; RADIATIVE RELAXATION; DRUG-DELIVERY; MECHANISMS; EUMELANIN; CHEMISTRY;

D O I：

10.1039/d0bm01070g

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Polydopamine (PDA) is the most typical kind of synthetic melanin, which possesses interesting properties such as antioxidation, photoprotection, metal chelation, and energy dissipation. Over the past few years, PDA has been successfully synthesizedviapolymerization methods and has demonstrated excellent free radical scavenging ability. The related applications have been rapidly expanded to include sunscreens, anti-inflammatory treatment, and composite material fabrication. Despite great progress, the comprehensive mechanisms of its free radical scavenging behaviors are not fully understood. This article strives to summarize the possible mechanisms, established antioxidant regulation methods and the related biomedical applications of PDA free radical scavengers. We believe this paper can provide insight into the current PDA scavenging systems and offer inspiration towards the design of new melanin-inspired scavengers with a broad range of biomedical applications.

引用

页码：4940 / 4950

页数：11

共 94 条

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