A New Diterpene Isolated from the Resin of Hymenaea Courbaril

被引:3
作者
Bandeira, P. N. [1 ]
Santos, H. S. [1 ]
Albuquerque, M. R. J. R. [1 ]
Lemos, T. L. G. [2 ]
Braz-Filho, R. [3 ]
机构
[1] State Univ Valley Acarau, Ctr Sci & Technol, BR-62040370 Sobral Ce, Brazil
[2] Univ Fed Ceara, Dept Organ & Inorgan Chem, BR-60451970 Fortaleza, Ceara, Brazil
[3] State Univ North Fluminense Darcy Ribeiro, CCT, Lab Chem Sci, BR-28013602 Campos, RJ, Brazil
关键词
Hymenaea courbaril; resin; diterpene; labdane; NMR data;
D O I
10.1007/s10600-015-1386-5
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Hymenaea courbaril, a traditional medicinal plant from Brazil, produces a resin rich in terpenoid compounds, mainly diterpenes. The resin and others parts are used in folk medicine for treatment of several pathologies. Fractionation of the resin by silica gel open column chromatography afforded two compounds: (5S,9S,10R)-ent-labd-8(17)-en-15 ethyl acetate (1) and copalic acid [5-(2-methylene-5,5,8atrimethyl-(1R,4aR,8aR)-decahydronaphthalen-1-yl)-3-methylpent-2E-enoic acid] (2). This is the first report of compound 1.
引用
收藏
页码:693 / 696
页数:4
相关论文
共 12 条
[1]   Bioactive diterpenes from the fruits of Detarium microcarpum [J].
Cavin, Anne-Laure ;
Hay, Anne-Emmanuelle ;
Marston, Andrew ;
Stoeckli-Evans, Helen ;
Scopelliti, Rosario ;
Diallo, Drissa ;
Hostettmann, Kurt .
JOURNAL OF NATURAL PRODUCTS, 2006, 69 (05) :768-773
[2]  
Fernandes T. T., 2005, Revista de Patologia Tropical, V34, P113
[3]  
Gonçalves A.L., 2005, Arq. Inst. Biol., V72, P353
[4]  
Lee Y., 1975, SYSTEMATICS GENUS HY
[5]   Kaurane Diterpenoids from Celastrus orbiculatus [J].
Li, Jian-Juan ;
Yang, Jie ;
Wu, Fei-Hua ;
Wang, Shan-Shan ;
Wang, Qiang .
CHEMISTRY OF NATURAL COMPOUNDS, 2014, 49 (06) :1032-1034
[6]  
Lorenzi H., 2002, Plantas medicinais no Brasil: nativas e exoticas
[7]  
Lorenzi H, 2000, Arvores Brasileiras: manual de identificacao e cultivo de planta arboreas nativas do Brasil, P347
[8]  
Martins CHG., 2010, INVESTIGACAO, V10, P37
[9]  
Neves M. C. A., 1993, PHYTOTHER RES, V75, P356
[10]   A new ent-kaurane diterpenoid from Rubus corchorifolius [J].
Ou, Yang-Wen ;
Chen, Xue-Xiang ;
Zhang, Min ;
Liu, Xiao-Juan ;
Cao, Yong .
CHEMISTRY OF NATURAL COMPOUNDS, 2013, 48 (06) :999-1001