The environmental influence on the photoluminescence behavior of thiol-capped CdTe quantum dots in living cells

被引:0
作者
Zhang, Yu [1 ]
Mi, Lan [1 ]
Chen, Ji-Yao [2 ]
Wang, Pei-Nan [1 ]
机构
[1] Fudan Univ, Dept Opt Sci & Engn, Shanghai 200433, Peoples R China
[2] Fudan Univ, Dept Phys, Shanghai 200433, Peoples R China
基金
中国国家自然科学基金;
关键词
AQUEOUS-SOLUTIONS; LIVE CELLS; BIOLOGICAL DETECTION; SINGLET OXYGEN; NANOCRYSTALS; PH; PHOTOOXIDATION; PHOTOSTABILITY; PHOTOACTIVATION; NANOPARTICLES;
D O I
10.1088/1748-6041/4/1/012001
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Water-soluble colloidal semiconductor quantum dots (QDs) as a new class of fluorescent probes with excellent optical properties have attracted considerable attention in bioapplications. Because of the large surface-to-volume ratio of QDs, especially in the case of QDs passivated with organic ligands, the photoluminescence (PL) of QDs is sensitive to the environmental conditions. Generally, the PL behavior of intracellular QDs is more complicated than that in solutions due to the complex cellular environment. In this review, the environmental influence on the PL behavior of intracellular thiol-capped CdTe QDs, such as the time-dependent spectral blueshift, photobleaching and lifetime shortening, is introduced and its mechanisms are discussed.
引用
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页数:9
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共 55 条
[1]   Size-dependent dissociation pH of thiolate ligands from cadmium chalcogenide nanocrystals [J].
Aldana, J ;
Lavelle, N ;
Wang, YJ ;
Peng, XG .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (08) :2496-2504
[2]   The use of nanocrystals in biological detection [J].
Alivisatos, P .
NATURE BIOTECHNOLOGY, 2004, 22 (01) :47-52
[3]   Implications of the generation of reactive oxygen species by photoactivated calcein for mitochondrial studies [J].
Beghetto, C ;
Renken, C ;
Eriksson, O ;
Jori, G ;
Bernardi, P ;
Ricchelli, F .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 2000, 267 (17) :5585-5592
[4]   Semiconductor nanocrystals as fluorescent biological labels [J].
Bruchez, M ;
Moronne, M ;
Gin, P ;
Weiss, S ;
Alivisatos, AP .
SCIENCE, 1998, 281 (5385) :2013-2016
[5]   Luminescent quantum dots for multiplexed biological detection and imaging [J].
Chan, WCW ;
Maxwell, DJ ;
Gao, XH ;
Bailey, RE ;
Han, MY ;
Nie, SM .
CURRENT OPINION IN BIOTECHNOLOGY, 2002, 13 (01) :40-46
[6]   Quantum dot bioconjugates for ultrasensitive nonisotopic detection [J].
Chan, WCW ;
Nie, SM .
SCIENCE, 1998, 281 (5385) :2016-2018
[7]   Individual acidic organelle pH measurements by capillary electrophoresis [J].
Chen, Y ;
Arriaga, EA .
ANALYTICAL CHEMISTRY, 2006, 78 (03) :820-826
[8]   Long-term exposure to CdTe quantum dots causes functional impairments in live cells [J].
Cho, Sung Ju ;
Maysinger, Dusica ;
Jain, Manasi ;
Roder, Beate ;
Hackbarth, Steffen ;
Winnik, Francoise M. .
LANGMUIR, 2007, 23 (04) :1974-1980
[9]   Optical sectioning microscopy [J].
Conchello, JA ;
Lichtman, JW .
NATURE METHODS, 2005, 2 (12) :920-931
[10]   Diffusion dynamics of glycine receptors revealed by single-quantum dot tracking [J].
Dahan, M ;
Lévi, S ;
Luccardini, C ;
Rostaing, P ;
Riveau, B ;
Triller, A .
SCIENCE, 2003, 302 (5644) :442-445