Multiorgan dysfunction and disseminated intravascular coagulation in children receiving lamotrigine and valproic acid

被引：41
作者：
Chattergoon, DS
McGuigan, MA
Koren, G
Hwang, P
Ito, S
机构：
[1] HOSP SICK CHILDREN,DIV CLIN PHARMACOL & TOXICOL,TORONTO,ON M5G 1X8,CANADA
[2] HOSP SICK CHILDREN,DIV NEUROL,TORONTO,ON M5G 1X8,CANADA
[3] HOSP SICK CHILDREN,DEPT PEDIAT,TORONTO,ON M5G 1X8,CANADA
[4] UNIV TORONTO,DEPT PHARMACOL,TORONTO,ON,CANADA
来源：
NEUROLOGY | 1997年 / 49卷 / 05期
关键词：
D O I：
10.1212/WNL.49.5.1442
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Two children developed multiorgan dysfunction with dis seminated intravascular coagulation 9 days after lamotrigine was added to their antiepileptic therapy, which included valproic acid. During the episodes, rhabdomyolysis was detected in one of them, while being seizure-free, suggesting that this adverse reaction may involve muscular tissue.
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收藏
页码：1442 / 1444
页数：3
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