Water-soluble resorcin[4]arene: Complexation of anionic aromatic guests by cooperativity of electrostatic and hydrophobic interactions

被引：36

作者：

Ahn, DR ^{[1
]}

Kim, TW ^{[1
]}

Hong, JI ^{[1
]}

机构：

[1] Seoul Natl Univ, Dept Chem, Seoul 151742, South Korea

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 33期

基金：

新加坡国家研究基金会;

关键词：

noncovalent interaction; water-soluble resorcin[4]arene; cooperativity; complexation;

D O I：

10.1016/S0040-4039(99)01227-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Water-soluble resorcin[4]arene based cavitand 2 was synthesized by reaction of bromomethylcavitand 1 with hexamethylenetetramine. The bowl-shaped cavitand host 2 shows a good binding affinity to anionic aromatic guests with 1:1 binding in D2O. The guest inclusion within the host cavity was confirmed by H-1 NMR spectroscopy. Electrostatic interaction as well as hydrophobic interaction turned out to cooperatively act as binding forces for a strong complex formation in water. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：6045 / 6048

页数：4

共 29 条

[1] CONFORMATIONAL-ANALYSIS .130. MM2 - HYDROCARBON FORCE-FIELD UTILIZING V1 AND V2 TORSIONAL TERMS [J].