Mechanosynthesis of γ-nitro dicarbonyl compounds via CaCl2-catalyzed Michael addition

被引：9

作者：

Jia, Chunman ^{[1
,2
]}

Chen, Da ^{[1
]}

Zhang, Chunyan ^{[1
]}

Zhang, Qi ^{[1
,2
]}

Cao, Bennan ^{[1
]}

Zhao, Zhendong ^{[1
]}

机构：

[1] Hainan Univ, Hainan Prov Key Lab Fine Chemials, Haikou 570228, Peoples R China

[2] Hainan Univ, Natl Minist Educ Trop Resources Utilizat, Key Study Ctr, Haikou 570228, Peoples R China

来源：

TETRAHEDRON | 2013年 / 69卷 / 35期

基金：

中国国家自然科学基金;

关键词：

Mechanosynthesis; Ball-milling; gamma-Nitro carbonyl esters; Michael addition; SOLVENT-FREE SYNTHESIS; 1,3-DICARBONYL COMPOUNDS; AZACHALCONES; REACTIVITY; CHALCONES; ALDEHYDES;

D O I：

10.1016/j.tet.2013.06.089

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient strategy for the mechanosynthesis of gamma-nitro dicarbonyl esters has been developed. A CaCl2-catalyzed Michael reaction, conducted at room temperature, afforded nitroalkenes from malonates in a short reaction time and in high yields. In most cases, polymerized side-reactions are eliminated or minimized. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：7320 / 7324

页数：5

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