Clinically Approved Nanoparticle Imaging Agents

被引:169
作者
Thakor, Avnesh S. [1 ]
Jokerst, Jesse V. [2 ]
Ghanouni, Pejman [1 ]
Campbell, Jos L. [1 ]
Mittra, Erik [1 ]
Gambhir, Sanjiv S. [1 ]
机构
[1] Stanford Univ, Med Ctr, Dept Radiol, Stanford, CA 94305 USA
[2] Univ Calif San Diego, Dept Nano Engn, San Diego, CA 92103 USA
关键词
nanoparticles; medical imaging; molecular imaging; nanoparticle; imaging and diagnostics; LYMPH-NODE BIOPSY; FLUORESCENT INDOCYANINE GREEN; TC-99M; SCINTIGRAPHY; DIAGNOSIS;
D O I
10.2967/jnumed.116.181362
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Nanoparticles are a new class of imaging agent used for both anatomic and molecular imaging. Nanoparticle-based imaging exploits the signal intensity, stability, and biodistribution behavior of submicron-diameter molecular imaging agents. This review focuses on nanoparticles, used in human medical imaging, with an emphasis on radionuclide imaging and MRI. Newer nanoparticle platforms are also discussed in relation to theranostic and multimodal uses.
引用
收藏
页码:1833 / 1837
页数:5
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