A ratiometric merocyanine-based fluorescent probe for detecting hydrazine in living cells and zebra fish

被引：41
作者：
Han, Jinliang [1 ]
Yue, Xiuxiu [1 ]
Wang, Jingpei [1 ]
Zhang, Yun [1 ]
Wang, Benhua [1 ]
Song, Xiangzhi [1 ,2 ]
机构：
[1] Cent South Univ, Coll Chem & Chem Engn, Changsha 410083, Peoples R China
[2] Key Lab Hunan Prov Water Environm & Agr Prod Safe, Changsha 410083, Peoples R China
来源：
CHINESE CHEMICAL LETTERS | 2020年 / 31卷 / 06期
基金：
中国国家自然科学基金;
关键词：
Fluorescent probe; Hydrazine; Merocyanine; Ratiometric; Cell imaging; TURN-ON PROBE; SELECTIVE DETECTION; ACID;
D O I：
10.1016/j.cclet.2020.01.029
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We developed a merocyanine-based fluorescent probe, NEPB, for tracing hydrazine (N2H4) in a ratiometric manner with large Stokes shifts and long emission wavelength. The fluorescence color of probe NEPB changed from green to yellow upon addition of hydrazine. Probe NEPB displayed high selectivity and sensitivity to hydrazine in solution, and could ratiometrically monitor N2H4 in living cells and zebrafish with low cytotoxicity. (c) 2020 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码：1508 / 1510
页数：3
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