Functionalization of pyrrolo[2,3-d]pyrimidine by palladium-catalyzed cross-coupling reactions (review)

被引：43

作者：

Tumkevicius, S. ^{[1
]}

Dodonova, J. ^{[1
]}

机构：

[1] Vilnius Univ, LT-03225 Vilnius, Lithuania

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2012年 / 48卷 / 02期

关键词：

pyrrolo[2,3-d]pyrimidine; biological activity; cyclization; fluorescence; Heck reaction; palladium catalysis; Sonogashira reaction; Stille reaction; Suzuki reaction; ADENOSINE-KINASE-INHIBITORS; BETA-L-RIBONUCLEOSIDES; NUCLEOSIDE TRIPHOSPHATES; THYMIDYLATE SYNTHASE; DIHYDROFOLATE-REDUCTASE; EFFICIENT SYNTHESIS; ENZYME-INHIBITION; DUPLEX STABILITY; ECHIGUANINE-A; DNA;

D O I：

10.1007/s10593-012-0986-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed cross-coupling reactions (Heck, Sonogashira, Stille, Suzuki) in the pyrrolo-[2,3-d]pyrimidine series with emphasis on synthesis of biologically active and functional materials are reviewed.

引用

收藏

页码：258 / 279

页数：22

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