Metal-free arylation of benzene and pyridine promoted by amino-linked nitrogen heterocyclic carbenes

被引：115

作者：

Chen, Wen-Ching ^{[1
]}

Hsu, Yu-Chen ^{[1
,2
]}

Shih, Wei-Chun ^{[1
]}

Lee, Ching-Yu ^{[1
,3
]}

Chuang, Wen-Han ^{[1
,4
]}

Tsai, Yi-Fang ^{[1
]}

Chen, Peter Ping-Yu ^{[5
]}

Ong, Tiow-Gan ^{[1
]}

机构：

[1] Acad Sinica, Inst Chem, Taipei, Taiwan

[2] Natl Taipei Univ Technol, Inst Organ & Polymer Mat, Taipei, Taiwan

[3] Taipei Municipal Univ Educ, Taipei, Taiwan

[4] Tamkang Univ, Dept Chem, Taipei, Taiwan

[5] Natl Chung Hsing Univ, Dept Chem, Taichung, Taiwan

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 53期

关键词：

SINGLE-ELECTRON-TRANSFER; C-H ACTIVATION; ARYL HALIDES; NUCLEOPHILIC-SUBSTITUTION; UNACTIVATED ARENES; PHENOL ETHERS; ORGANOCATALYSIS; BUTOXIDE; ALKOXIDES;

D O I：

10.1039/c2cc32519e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An amino-linked nitrogen heterocyclic carbene (amino-NHC), 1-tBu, has been shown to mediate carbon-carbon coupling through the direct C-H functionalization of benzene and pyridine in the absence of a metal catalyst. Using EPR, the first spectroscopic evidence corroborating the single electron transfer mechanism for the metal-free carbon-carbon coupling manifold, as reported by others, is introduced.

引用

页码：6702 / 6704

页数：3

共 28 条

[1] Deprotonation of N-heterocyclic carbenes to afford heterobimetallic organolanthanide complexes [J].