Neurolymphomatosis as a late relapse of non-Hodgkin's lymphoma detected by 18F-FDG PET/CT: A case report

被引：5
作者：
Kajary, K. [1 ]
Molnar, Z. [2 ]
Miko, I. [3 ]
Barsi, P. [4 ]
Lengyel, Z. [1 ]
Szakall, S., Jr. [1 ]
机构：
[1] Pozitron PET CT Ctr, Budapest, Hungary
[2] Natl Inst Oncol, Budapest, Hungary
[3] Natl Inst Rheumatism & Physiotherapy, Budapest, Hungary
[4] Semmelweis Univ, MR Res Ctr, H-1085 Budapest, Hungary
来源：
REVISTA ESPANOLA DE MEDICINA NUCLEAR E IMAGEN MOLECULAR | 2014年 / 33卷 / 01期
关键词：
Neurolymphomatosis; Non-Hodgkin's lymphoma; Diffuse large B-cell lymphoma; FDG; PET/CT; FDG-PET; CHEMOTHERAPY; DIAGNOSIS; CT;
D O I：
10.1016/j.remn.2013.03.004
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Neurolymphomatosis is a rare condition defined as an infiltration of nerves, nerve roots or nervous plexuses by haematological malignancy. Its diagnosis may sometimes be difficult with conventional imaging techniques. This paper aims to emphasize the importance of this entity and the role of F-18-FDG PET/CT in this indication. We present the case of a 53-year-old male who complained of sharp pain in his right hip and right leg paresthesia after 2 years of complete remission from Non-Hodgkin's lymphoma. Physical examination and CT scan were negative and the lumbar MRI showed protrusion of L5-S1 disc. Physiotherapy, nonsteroid antiinflammatory drugs and steroids were inefficient. PET/CT was performed four months after the onset of the symptoms, revealing focal FOG uptake in the right S1 nerve root and linear FDG uptake along the right sacral plexus suggesting relapse. This was confirmed by histology. (C) 2013 Elsevier Espana, S.L. and SEMNIM. All rights reserved.
引用
收藏
页码：39 / 42
页数：4
相关论文
共 11 条
[1]   Positron Emission Tomographic Scans in Lymphoma: Convention and Controversy [J].
Ansell, Stephen M. ;
Armitage, James O. .
MAYO CLINIC PROCEEDINGS, 2012, 87 (06) :571-580
[2]  
Cook GJR, 2007, Q J NUCL MED MOL IM, V51, P235
[3]   Neurolymphomatosis: Diagnosis of extension and assessment of response to treatment with PET-CT [J].
Duran, C. ;
Infante, J. R. ;
Serrano, J. ;
Rayo, J. I. ;
Garcia, L. ;
Dominguez, M. L. ;
Sanchez, R. .
REVISTA ESPANOLA DE MEDICINA NUCLEAR, 2009, 28 (06) :295-298
[4]   Neurolymphomatosis: an International Primary CNS Lymphoma Collaborative Group report [J].
Grisariu, Sigal ;
Avni, Batia ;
Batchelor, Tracy T. ;
van den Bent, Martin J. ;
Bokstein, Felix ;
Schiff, David ;
Kuittinen, Outi ;
Chamberlain, Marc C. ;
Roth, Patrick ;
Nemets, Anatoly ;
Shalom, Edna ;
Ben-Yehuda, Dina ;
Siegal, Tali .
BLOOD, 2010, 115 (24) :5005-5011
[5]   Neurolymphomatosis - diagnosis and assessment of treatment response by FDG PET-CT [J].
Lin, M. ;
Kilanowska, J. ;
Taper, J. ;
Chu, J. .
HEMATOLOGICAL ONCOLOGY, 2008, 26 (01) :43-45
[6]   FDG-PET after two to three cycles of chemotherapy predicts progression-free and overall survival in high-grade non-Hodgkin lymphoma [J].
Mikhaeel, NG ;
Hutchings, M ;
Fields, PA ;
O'Doherty, MJ ;
Timothy, AR .
ANNALS OF ONCOLOGY, 2005, 16 (09) :1514-1523
[7]   Increasing importance of 18F-FDG PET in the diagnosis of neurolymphomatosis [J].
Salm, Liesbeth P. ;
Van der Hiel, Bernies ;
Stokkel, Marcel P. M. .
NUCLEAR MEDICINE COMMUNICATIONS, 2012, 33 (09) :907-916
[8]   Sciatic nerve neurolymphomatosis - Extent and therapy response assessment with PET/CT [J].
Strobel, Klaus ;
Fischer, Katharina ;
Hany, Thomas F. ;
Poryazova, Rositsa ;
Jung, Hans H. .
CLINICAL NUCLEAR MEDICINE, 2007, 32 (08) :646-648
[9]   F-18 FDG PET/CT Findings of a Case of Sacral Nerve Root Neurolymphomatosis That Occurred During Chemotherapy [J].
Suga, Kazuyoshi ;
Yasuhiko, Kawakami ;
Matsunaga, Naofumi ;
Yujiri, Toshiaki ;
Nakazora, Tatsuki ;
Ariyoshi, Kouichi .
CLINICAL NUCLEAR MEDICINE, 2011, 36 (01) :73-76
[10]   Fusion PET-CT detection of neurolymphomatosis originating from primary breast lymphoma: A case report and literature review [J].
Xu, Liying ;
Zhou, Yunfeng ;
Qiu, Dasheng ;
Shams, Salman .
ONCOLOGY LETTERS, 2012, 4 (05) :973-975
12