Restricted Adipogenesis in Hypertrophic Obesity The Role of WISP2, WNT, and BMP4

被引:114
作者
Gustafson, Birgit [1 ]
Hammarstedt, Ann [1 ]
Hedjazifar, Shahram [1 ]
Smith, Ulf [1 ]
机构
[1] Gothenburg Univ, Sahlgrenska Acad, Ctr Excellence Metab & Cardiovasc Res, Dept Mol & Clin Med,Lab Diabet Res, Gothenburg, Sweden
基金
瑞典研究理事会;
关键词
ADIPOSE-TISSUE; INSULIN-RESISTANCE; METABOLICALLY HEALTHY; ABDOMINAL OBESITY; FAT; RISK; DIFFERENTIATION; COMMITMENT; IDENTIFICATION; LIPOTOXICITY;
D O I
10.2337/db13-0473
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:2997 / 3004
页数:8
相关论文
共 57 条
  • [1] Adipocyte Hypertrophy, Fatty Liver and Metabolic Risk Factors in South Asians: The Molecular Study of Health and Risk in Ethnic Groups (mol-SHARE)
    Anand, Sonia S.
    Tarnopolsky, Mark A.
    Rashid, Shirya
    Schulze, Karleen M.
    Desai, Dipika
    Mente, Andrew
    Rao, Sandy
    Yusuf, Salim
    Gerstein, Hertzel C.
    Sharma, Arya M.
    [J]. PLOS ONE, 2011, 6 (07):
  • [2] Adipocyte Turnover: Relevance to Human Adipose Tissue Morphology
    Arner, Erik
    Westermark, Pal O.
    Spalding, Kirsty L.
    Britton, Tom
    Ryden, Mikael
    Frisen, Jonas
    Bernard, Samuel
    Arner, Peter
    [J]. DIABETES, 2010, 59 (01) : 105 - 109
  • [3] Variations in the Size of the Major Omentum Are Primarily Determined by Fat Cell Number
    Arner, Peter
    Andersson, Daniel Peter
    Thorne, Anders
    Wiren, Mikael
    Hoffstedt, Johan
    Naslund, Erik
    Thorell, Anders
    Ryden, Mikael
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2013, 98 (05) : E897 - E901
  • [4] Genetic Predisposition for Type 2 Diabetes, but Not for Overweight/Obesity, Is Associated with a Restricted Adipogenesis
    Arner, Peter
    Arner, Erik
    Hammarstedt, Ann
    Smith, Ulf
    [J]. PLOS ONE, 2011, 6 (04):
  • [5] Stable stem cell commitment to the adipocyte lineage by inhibition of DNA methylation: Role of the BMP-4 gene
    Bowers, Robert R.
    Kim, Jae Woo
    Otto, Tamara C.
    Lane, M. Daniel
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (35) : 13022 - 13027
  • [6] Insulin Resistance and Body Fat Distribution in South Asian Men Compared to Caucasian Men
    Chandalia, Manisha
    Lin, Ping
    Seenivasan, Thanalakshmi
    Livingston, Edward H.
    Snell, Peter G.
    Grundy, Scott M.
    Abate, Nicola
    [J]. PLOS ONE, 2007, 2 (08):
  • [7] The Wnt antagonist Dickkopf-1 and its receptors are coordinately regulated during early human adipogenesis
    Christodoulides, Constantinos
    Laudes, Matthias
    Cawthorn, Will P.
    Schinner, Sven
    Soos, Maria
    O'Rahilly, Stephen
    Sethi, Jaswinder K.
    Vidal-Puig, Antonio
    [J]. JOURNAL OF CELL SCIENCE, 2006, 119 (12) : 2613 - 2620
  • [8] Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
    Cinti, S
    Mitchell, G
    Barbatelli, G
    Murano, I
    Ceresi, E
    Faloia, E
    Wang, SP
    Fortier, M
    Greenberg, AS
    Obin, MS
    [J]. JOURNAL OF LIPID RESEARCH, 2005, 46 (11) : 2347 - 2355
  • [9] Wnt/β-Catenin Signaling and Disease
    Clevers, Hans
    Nusse, Roel
    [J]. CELL, 2012, 149 (06) : 1192 - 1205
  • [10] Role of Obesity and Lipotoxicity in the Development of Nonalcoholic Steatohepatitis: Pathophysiology and Clinical Implications
    Cusi, Kenneth
    [J]. GASTROENTEROLOGY, 2012, 142 (04) : 711 - U109