ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil

被引：8
作者：
Thabet, F
Sghiri, R
Tabarki, B
Ghedira, I
Yacoub, M
Essoussi, AS
机构：
[1] Hosp Farhat Hached, Serv Pediat, Sousse 4000, Tunisia
[2] Hosp Farhat Hached, Dept Immunol, Sousse 4000, Tunisia
[3] Hosp Farhat Hached, Dept Pediat, Sousse 4000, Tunisia
来源：
EUROPEAN JOURNAL OF PEDIATRICS | 2006年 / 165卷 / 07期
关键词：
antineutrophil cytoplasmic antibody; vasculitis; diffuse alveolar hemorrhage; benzylthiouracil;
D O I：
10.1007/s00431-005-0053-4
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Benzylthiouracil has been recently observed to be associated with antineutrophil cytoplasmic antibody-positive vasculitis, resulting in crescentic glomerulonephritis. We report an 8-year-old girl treated with benzylthiouracil for Graves's disease who developed an ANCA-positive vasculitis with pulmonary hemorrhage. She responded to corticosteroids and discontinuation of benzylthiouracil. This represents the first pediatric case of benzylthiouracil-induced diffuse alveolar hemorrhage.
引用
收藏
页码：435 / 436
页数：2
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