Electrocardiogram signs of right ventricular hypertrophy may help identify pulmonary hypertension in patients with dilated cardiomyopathy

被引:6
作者
Chen, Chengzhi [1 ]
Liu, Jingyan [1 ]
Liu, Zhiyong [1 ]
He, Xin [1 ]
Yuan, Xuming [1 ]
Ouyang, Xiufen [1 ]
Wang, Lei [1 ]
Li, Xiaoping [2 ,3 ]
机构
[1] Liuyang People Hosp, Dept Cardiol, Liuyang 410300, Peoples R China
[2] Sichuan Acad Med Sci, Dept Cardiol, Chengdu 610072, Sichuan, Peoples R China
[3] Sichuan Prov Peoples Hosp, Chengdu 610072, Sichuan, Peoples R China
来源
IJC HEART & VASCULATURE | 2019年 / 22卷
基金
中国国家自然科学基金;
关键词
Dilated cardiomyopathy; Pulmonary hypertension; Right ventricular hypertrophy; ECG; LEFT-HEART DISEASE; INTERNATIONAL-SOCIETY; ECHOCARDIOGRAPHY; RECOMMENDATIONS; STATEMENT; SECONDARY; COMMITTEE; COUNCIL; UTILITY;
D O I
10.1016/j.ijcha.2018.12.006
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To the authors' knowledge, limited data are available regarding the association between Electrocardiogram (ECG) signs of right ventricular hypertrophy (RVH) and pulmonary hypertension (PH) in patients with dilated cardiomyopathy (DCM). We aimed to assess the accuracy of the recommended ECG criteria of RVH for predicting PH in patients with DCM. Methods: According to the definition of PH (mPAP >= 25 mm Hg), 35 patients with DCM were divided into 2 groups: DCM with PH (n = 22) and DCM without PH (n = 13). Right heart catheterization was performed in all patients. Seventeen parameters of RVH recommended by the AHA/ACCF/HRS for diagnosis of RVH on ECG were determinded. Results: The following parameters were correlated with mPAP: R-V1 > 6 mm, S-V5 > 10 mm, R:S-V6 < 0.4, R-V1 + S-V5 (or V6) > 10.5 mm and P-II amplitude. The following parameters were significantly different between DCM patients with and without PH: S in V-5 (S-V5) > 10 mm, S in V-6 (S-V6) > 3 mm, R:S ratio in V-5 (R:S-V5) < 0.75, R-V1 + S-V5 or V6 > 10.5 mm, S > R inI, S > R inII and R:S (V1) > R:S (V3), although results were no longer significant after correcting for multiple comparisons. High specificity (92.3-100%), lowsensitivity (31.8-50%), high positive predictive value, and low negative predictive value of established parameters of RVH were noted for predicting PH in patients with DCM. Conclusion: Several ECG signs of RVH may be useful for in the diagnosis PH in patients with DCM. (c) 2019 The Authors. Published by Elsevier B.V.
引用
收藏
页码:61 / 66
页数:6
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