Four new sesquiterpenes from the stems of Pogostemon cablin

被引：21

作者：

Li, Fei ^{[1
,2
]}

Li, Chuang-Jun ^{[1
,2
]}

Ma, Jie ^{[1
,2
]}

Yang, Jing-Zhi ^{[1
,2
]}

Chen, Hui ^{[1
,2
]}

Liu, Xi-Ming ^{[3
]}

Li, Yan ^{[1
,2
]}

Zhang, Dong-Ming ^{[1
,2
]}

机构：

[1] Chinese Acad Med Sci, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China

[2] Peking Union Med Coll, Beijing 100050, Peoples R China

[3] China Acad Chinese Med Sci, Guanganmen Hosp, Beijing 100053, Peoples R China

来源：

FITOTERAPIA | 2013年 / 86卷

基金：

中国国家自然科学基金;

关键词：

Pogostemon cablin; Sesquiterpene; Patchoulene; Guaiane; Hepatoprotective activity; ALPHA-BULNESENE; PATCHOULI OIL; CONSTITUENTS; FLAVONOIDS;

D O I：

10.1016/j.fitote.2013.03.010

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Four new sesquiterpenes (1-4), together with four known compounds (5-8), were isolated from the stems of Pogostemon cablin (Blanco.) Benth. Their chemical structures were elucidated by means of spectroscopic methods, including 1D and 2D NMR, HRESIMS, IR, and UV. Hepatoprotective activities of these compounds were investigated, by studying the protective effect on HL-7702 cellular injury induced by DL-galactosamine. (C) 2013 Elsevier B.V. All rights reserved.

引用

页码：183 / 187

页数：5

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