Platelet Counts and Coagulation Tests Prior to Neuraxial Anesthesia in Patients With Preeclampsia A Retrospective Analysis

被引:19
作者
Sultan, Pervez [1 ]
Butwick, Alexander [2 ]
机构
[1] Univ Coll London Hosp, Dept Anaesthesia, London NW1 2BU, England
[2] Stanford Univ, Dept Anesthesia, Sch Med, Stanford, CA 94305 USA
关键词
gynecology and obstetrics; preeclampsia; neuraxial anesthesia; thrombocytopenia; hemostasis; ELEVATED LIVER-ENZYMES; HELLP SYNDROME; HYPERTENSIVE DISORDERS; EPIDURAL ANALGESIA; PREGNANCY; HEMOLYSIS; MANAGEMENT; ECLAMPSIA; PATTERNS; DISEASE;
D O I
10.1177/1076029612441860
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This retrospective, descriptive study aimed to assess hematologic testing practices in 100 patients with preeclampsia undergoing neuraxial blockade (NB). Prior to NB, platelet (PLT) count was performed in 61 (98%) of 62 women in labor and in 37 (97%) of 38 women undergoing cesarean delivery (CD). No patients had a pre-NB PLT count < 70 x 10(9)/L. Pre-NB tests for prothrombin time (PT) and activated partial thromboplastin time (APTT) were less common and varied among laboring patients (15 [24%] of 62) and patients prior to CD (18 [47%] of 38). Prior to NB, PT and APTT values were within normal limits in all patients. The time intervals between laboratory testing and NB ranged from < 2 to > 12 hours. The lack of consistency in pre-NB coagulation testing and the variable time intervals between laboratory tests and NB may be due to a lack of consensus among anesthesiologists for determining "safe" hemostatic conditions for NB placement in patients with preeclampsia.
引用
收藏
页码:529 / 534
页数:6
相关论文
共 29 条
[1]   Accuracy of urine dipsticks, 2-h and 12-h urine collections for protein measurement as compared with the 24-h collection [J].
Abebe, J. ;
Eigbefoh, J. ;
Isabu, P. ;
Okogbenin, S. ;
Eifediyi, R. ;
Okusanya, B. .
JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2008, 28 (05) :496-500
[2]  
ACOG, 2002, INT J GYNECOL OBSTET, V78, P321
[3]  
[Anonymous], 2002, Obstetrics and Gynecology, V99, P159
[4]   COAGULATION SCREENING BEFORE EPIDURAL ANALGESIA IN PREECLAMPSIA [J].
BARKER, P ;
CALLANDER, CC .
ANAESTHESIA, 1991, 46 (01) :64-67
[5]   Reducing unnecessary coagulation testing in hypertensive disorders of pregnancy [J].
Barron, WM ;
Heckerling, P ;
Hibbard, JU ;
Fisher, S .
OBSTETRICS AND GYNECOLOGY, 1999, 94 (03) :364-370
[6]   Practice patterns of anesthesiologists regarding situations in obstetric anesthesia where clinical management is controversial [J].
Beilin, Y ;
Bodian, CA ;
Haddad, EM ;
Leibowitz, AB .
ANESTHESIA AND ANALGESIA, 1996, 83 (04) :735-741
[7]  
FitzGerald MP, 1996, J NATL MED ASSOC, V88, P794
[8]   Preeclampsia and anaesthesia [J].
Gogarten, Wiebke .
CURRENT OPINION IN ANESTHESIOLOGY, 2009, 22 (03) :347-351
[9]   Hemostatic abnormalities in patients with severe preeclampsia [J].
Heilmann, Lothar ;
Rath, Werner ;
Pollow, Kunhard .
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, 2007, 13 (03) :285-291
[10]  
Kramer RL, 1997, J REPROD MED, V42, P223